Evidence map›Paper›PMID 40942237›Full record

ArticlePolymers2025

Optimization of Chromium Removal Conditions from Tanned Leather Waste for Collagen Valorization.

Ana-Maria Nicoleta Codreanu Manea, Daniela Simina Stefan, Lidia Kim, Ionut Cristea, Rachid Aziam

Abstract read
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ana-Maria Nicoleta Codreanu ManeaFaculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.
Daniela Simina StefanFaculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.ORCID 0000-0002-9787-194X
Lidia KimNational Research and Development Institute for Industrial Ecology, 060652 Bucharest, Romania.ORCID 0000-0003-4252-6302
Ionut CristeaNational Research and Development Institute for Industrial Ecology, 060652 Bucharest, Romania.ORCID 0000-0003-1147-5928
Rachid AziamLaboratory of Applied Chemistry and Environment, Department of Chemistry, Faculty of Sciences, Ibnou Zohr University, Agadir BP 8106, Morocco.ORCID 0000-0002-8925-4351

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The large amounts of chrome-tanned leather waste (CLTW) produced annually can be valorized by applying circular economy principles in various fields due to the valuable substances contained (mainly collagen). The main problem for the direct valorization of these wastes is the presence in their composition of dangerous substances, such as chromium. Thus, before being used as raw material in new processes, chrome-tanned leather waste must be subjected to a preliminary stage of chromium removal. In this article, we propose to identify the optimal working conditions for the extraction of chromium ions from chrome-tanned hides in the presence of oxalic acid with various concentrations, at various temperatures and contact times, so that the degree of collagen hydrolysis is minimal. In this sense, the response surface methodology (RSM) method was used to optimize the working conditions, to maximize the efficiency of chrome extraction from the leather, and to minimize the efficiency of collagen hydrolysis: An undesirable process. To optimize both the extraction yield (%) and the degree of hydrolysis (%), the key operational variables, namely oxalic acid concentration (%), contact time (%), and temperature (°C), were systematically adjusted using the Box-Behnken design within the response surface methodology (RSM). The most favorable extraction conditions were identified at an oxalic acid concentration of approximately 7%, a contact time close to 120 min, and a temperature near 49 °C. Under these optimized parameters, the hydrolysis degree remained very low, around 0.38%, indicating minimal degradation during the process.

Indexed as

chromium removalcollagen hydrolysisleather waste treatmentoptimizationoxalic acid extractionresponse surface methodology (RSM)

Identifiers

PMID40942237
PMCPMC12431349

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.