Design and Evaluation of Indole-Based Schiff Bases as α-Glucosidase Inhibitors: CNN-Enhanced Docking, MD Simulations, ADMET Profiling, and SAR Analysis.
Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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5 · Who and what money
Authors and funding
10 authors.
Seema K BhagwatDepartment of Chemistry, Research Centre HPT Arts, RYK Science College (Affiliated to S. P. Pune University), Nashik 422005, Maharashtra, India.
Sachin V PatilDepartment of Chemistry, Research Centre HPT Arts, RYK Science College (Affiliated to S. P. Pune University), Nashik 422005, Maharashtra, India.
Abraham Vidal-LimonRed de Estudios Moleculares Avanzados, Instituto de Ecología, A. C., Carretera Antigua a Coatepec 351, Xalapa 91073, Veracruz, Mexico.ORCID 0000-0001-5674-7881
J Oscar C Jimenez-HallaDepartamento de Química, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Noria Alta S/N, Guanajuato 36050, Guanajuato, Mexico.ORCID 0000-0001-7354-3506
Balasaheb K GhotekarDepartment of Chemistry, Research Centre HPT Arts, RYK Science College (Affiliated to S. P. Pune University), Nashik 422005, Maharashtra, India.
Vivek D BobadeDepartment of Chemistry, Research Centre HPT Arts, RYK Science College (Affiliated to S. P. Pune University), Nashik 422005, Maharashtra, India.
Irving David Pérez-LandaDivisión de Estudios de Posgrado e Investigación, Tecnológico Nacional de México/Instituto Tecnológico de Boca del Río, Carretera Veracruz-Córdoba 12, Boca del Rio 94290, Veracruz, Mexico.ORCID 0000-0002-5240-5371
Enrique Delgado-AlvaradoMicro and Nanotechnology Research Center, Universidad Veracruzana, Blvd. Av. Ruiz Cortines No. 455 Fracc. Costa Verde, Boca del Rio 94294, Veracruz, Mexico.ORCID 0000-0002-6354-5222
Fabiola Hernández-RosasCentro de Investigación, Universidad Anáhuac Querétaro, El Marques 76246, Queretaro, Mexico.ORCID 0000-0003-2287-7041
Tushar Janardan PawarRed de Estudios Moleculares Avanzados, Instituto de Ecología, A. C., Carretera Antigua a Coatepec 351, Xalapa 91073, Veracruz, Mexico.ORCID 0000-0003-0753-9538
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
Type 2 diabetes mellitus (T2DM) remains a global health challenge, prompting the development of novel α-glucosidase inhibitors (AGIs) to regulate postprandial hyperglycemia. This study reports the design, synthesis, and evaluation of indole-based Schiff base derivatives (
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Design and Evaluation of Indole-Based Schiff Bases as α-Glucosidase Inhibitors: CNN-Enhanced Docking, MD Simulations, ADMET Profiling, and SAR Analysis. · full record | OpenQuestion