Evidence map›Paper›PMID 40942102›Full record

ReviewMolecules (Basel, Switzerland)2025

Modern Methods for Detection of Fentanyl and Its Analogues: A Comprehensive Review of Technologies and Applications.

Ewelina Bojarska, Wojciech Zajaczkowski, Elwira Furtak, Maksymilian Stela, Leslaw Gorniak, Marcin Podogrocki, Michal Bijak

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ewelina BojarskaDepartment of Protection Against Contamination, Military Institute of Chemistry and Radiometry, Antoniego Chrusciela "Montera" 105, 00-910 Warsaw, Poland.ORCID 0000-0002-2083-0277
Wojciech ZajaczkowskiBiohazard Prevention Centre, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.ORCID 0000-0003-0113-0985
Elwira FurtakDepartment of Protection Against Contamination, Military Institute of Chemistry and Radiometry, Antoniego Chrusciela "Montera" 105, 00-910 Warsaw, Poland.ORCID 0000-0001-7855-6736
Maksymilian StelaBiohazard Prevention Centre, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.
Leslaw GorniakBiohazard Prevention Centre, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.ORCID 0000-0001-9873-9521
Marcin PodogrockiBiohazard Prevention Centre, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.
Michal BijakBiohazard Prevention Centre, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.ORCID 0000-0002-7838-4097

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fentanyl and its analogues represent a severe threat due to their extreme potency and increasing prevalence in illicit drug supplies. Even trace amounts (on the order of a couple of milligrams) can be lethal, contributing to a surge in opioid overdose deaths worldwide. Beyond the public health crisis, fentanyl has emerged as a security concern, with the potential for deliberate use as a chemical agent in CBRN scenarios. This underscores the critical need for rapid and accurate detection methods that can be deployed by security forces and first responders. Modern technology offers a range of solutions-from portable mass spectrometers and spectroscopic devices to electrochemical sensors and immunoassay kits-that enable on-site identification of fentanyl and its analogues. This review provides a comprehensive overview of detection techniques, examining their capabilities and applications in law enforcement, border control, and CBRN incident response. We highlight how integration of advanced sensors with machine learning is enhancing detection accuracy in complex field environments. Challenges such as operational constraints and the ever-evolving variety of fentanyl analogues are discussed, and future directions are recommended to improve field-deployable detection tools for safety and security applications.

Indexed as

Analgesics, OpioidFentanylSubstance Abuse DetectionElectrochemical TechniquesHumansAnalgesics, OpioidFentanylaptamer biosensorsCBRNelectrochemical sensorsfentanyl detectionfield-deployable sensorsFTIRGC–MSLC–MS–MSRaman/SERS

Identifiers

PMID40942102
PMCPMC12430130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.