Evidence map›Paper›PMID 40942089›Full record

ArticleMolecules (Basel, Switzerland)2025

The Effect of 2'F-RNA on I-Motif Structure and Stability.

Cristina Ugedo, Arnau Domínguez, Irene Gómez-Pinto, Ramon Eritja, Carlos González, Anna Aviñó

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Enhanced i-Motif Stability through Consecutive 2',2'-Difluorocytidine Incorporation.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cristina UgedoInstituto de Química Física Blas Cabrera (IQF), CSIC, Serrano 119, 28006 Madrid, Spain.ORCID 0009-0009-7388-3610
Arnau DomínguezInstituto de Química Avanzada de Cataluña (IQAC), CSIC, Jordi Girona 18-26, 08034 Barcelona, Spain.ORCID 0000-0002-4336-9209
Irene Gómez-PintoInstituto de Química Física Blas Cabrera (IQF), CSIC, Serrano 119, 28006 Madrid, Spain.
Ramon EritjaInstituto de Química Avanzada de Cataluña (IQAC), CSIC, Jordi Girona 18-26, 08034 Barcelona, Spain.ORCID 0000-0001-5383-9334
Carlos GonzálezInstituto de Química Física Blas Cabrera (IQF), CSIC, Serrano 119, 28006 Madrid, Spain.ORCID 0000-0001-8796-1282
Anna AviñóInstituto de Química Avanzada de Cataluña (IQAC), CSIC, Jordi Girona 18-26, 08034 Barcelona, Spain.

Funding

CDTI-ISCIII PMTPA23/00008Spanish "Ministerio de Ciencia, Universidades e Innovación" PID2020-116620GB-I00, PID2023-146366NB-I00, PID2023-148655OB-I00
6 · The paper itself

Abstract

I-motifs are non-canonical, cytosine-rich DNA structures stabilized by hemiprotonated C•C

Indexed as

CytidineNucleotide MotifsRNABase PairingHydrogen-Ion ConcentrationMagnetic Resonance SpectroscopyNucleic Acid ConformationThermodynamicsCytidineRNAfluorine substitutioni-motifNMRnon-canonical nucleic acidsXNA

Identifiers

PMID40942089
PMCPMC12429874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.