Evidence map›Paper›PMID 40942075›Full record

ArticleMolecules (Basel, Switzerland)2025

Design, Synthesis, and In Vitro and In Silico Study of New Hybrid 1-(2-(4-Arylthiazol-2-yl)hydrazineylidene)-5,6-dihydro-4

Anna A Skoptsova, Athina Geronikaki, Anthi Petrou, Nadezhda P Novichikhina, Nadezhda A Podoplelova, Georgii A Bykov, Aleksandr A Anis'kov, Svetlana A Soloveva, Khidmet S Shikhaliev

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anna A SkoptsovaDepartment of Organic Chemistry, Faculty of Chemistry, Voronezh State University, 1 Universitetskaya Sq., 394018 Voronezh, Russia.ORCID 0000-0002-9859-6476
Athina GeronikakiSchool of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0001-9894-7777
Anthi PetrouSchool of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0001-8587-2710
Nadezhda P NovichikhinaDepartment of Organic Chemistry, Faculty of Chemistry, Voronezh State University, 1 Universitetskaya Sq., 394018 Voronezh, Russia.ORCID 0000-0001-8167-6093
Nadezhda A PodoplelovaCenter for Theoretical Problems of Physicochemical Pharmakology, 119991 Moscow, Russia.ORCID 0000-0001-8013-1112
Georgii A BykovCenter for Theoretical Problems of Physicochemical Pharmakology, 119991 Moscow, Russia.ORCID 0000-0002-5623-723X
Aleksandr A Anis'kovR&D Department, VIC Animal Health, VIC Group, 308570 Belgorod, Russia.ORCID 0000-0002-6459-1511
Svetlana A SolovevaNesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 119334 Moscow, Russia.ORCID 0000-0003-2821-6252
Khidmet S ShikhalievDepartment of Organic Chemistry, Faculty of Chemistry, Voronezh State University, 1 Universitetskaya Sq., 394018 Voronezh, Russia.ORCID 0000-0002-6576-0305

Funding

The research was funded by the Ministry of Science and Higher Education of the Russian Federation within the framework of State Contract with universities regarding scientific research in 2023-2025 Project № FZGU-2023-0009
6 · The paper itself

Abstract

To develop efficient and structurally novel anticoagulants, a library of new hybrid molecules-(Z)-1-(2-(4-arylthiazol-2-yl)hydrazineylidene)-5,6-dihydro-4H-pyrrolo[3,2,1-

Indexed as

AnticoagulantsDrug DesignFactor XaFactor Xa InhibitorsFactor XIaQuinolonesHumansMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipAnticoagulantsFactor XaFactor Xa InhibitorsFactor XIaQuinolonesanticoagulantfactor Xafactor XIainhibitorsmolecular dockingpyrrolo[3,2,1-ij]quinolin-2-onethiazole

Identifiers

PMID40942075
PMCPMC12430708

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.