GABAergic and α-Glucosidase-Inhibitory Potentials of Fractions and Isolated Xanthones from

Maria S Chukwuma, Lorenza Bertaina, Sophia Khom, Chika I Chukwuma, Pieter C Zietsman, Anke Wilhelm, Susanna L Bonnet

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria S ChukwumaDepartment of Chemistry, Faculty of Natural and Agricultural Sciences, University of the Free State, Bloemfontein 9301, South Africa.ORCID 0000-0002-0014-4130

Lorenza BertainaDepartment of Pharmaceutical Sciences, Faculty of Life Sciences, University of Vienna, 1090 Vienna, Austria.

Sophia KhomDepartment of Pharmaceutical Sciences, Faculty of Life Sciences, University of Vienna, 1090 Vienna, Austria.

Chika I ChukwumaCenter for Quality of Health and Living (CQHL), Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9301, South Africa.

Pieter C ZietsmanBloemfontein National Museum, Bloemfontein 9301, South Africa.

Anke WilhelmDepartment of Chemistry, Faculty of Natural and Agricultural Sciences, University of the Free State, Bloemfontein 9301, South Africa.ORCID 0000-0003-4561-5589

Susanna L BonnetDepartment of Chemistry, Faculty of Natural and Agricultural Sciences, University of the Free State, Bloemfontein 9301, South Africa.

Funding

University of the Free State N/A

6 · The paper itself

Abstract

This study aimed to investigate the glycaemic control potential and modulation of GABA-induced chloride currents (I

Indexed as

alpha-GlucosidasesGlycoside Hydrolase InhibitorsHypericumPlant ExtractsXanthonesAnimalsgamma-Aminobutyric AcidOocytesPlant LeavesReceptors, GABA-AXenopus laevisalpha-Glucosidasesgamma-Aminobutyric AcidGlycoside Hydrolase InhibitorsPlant ExtractsReceptors, GABA-AXanthonesGABAA receptorH. revolutumIGABA modulationxanthonesα-glucosidase inhibition

Identifiers

PMID40942057

DOI10.3390/molecules30173530

PMCPMC12430133

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.