Evidence map›Paper›PMID 40941564›Full record

ArticleHealthcare (Basel, Switzerland)2025

Quality of Life in Short Stature: Comparisons Between Normal Variants Short-Statured and Normal-Statured Children and Adolescents and Agreement with Their Parents.

Anna Guerrini Usubini, Nicoletta Marazzi, Laura Abbruzzese, Adele Bondesan, Graziano Grugni, Gianluca Castelnuovo, Alessandro Sartorio

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anna Guerrini UsubiniExperimental Laboratory for Auxo-Endocrinological Research, Istituto Auxologico Italiano, IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), 28824 Piancavallo-Verbania, Italy.
Nicoletta MarazziExperimental Laboratory for Auxo-Endocrinological Research, Istituto Auxologico Italiano, IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), 28824 Piancavallo-Verbania, Italy.
Laura AbbruzzeseDivision of Auxology, Istituto Auxologico Italiano, IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), 28824 Piancavallo-Verbania, Italy.
Adele BondesanExperimental Laboratory for Auxo-Endocrinological Research, Istituto Auxologico Italiano, IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), 28824 Piancavallo-Verbania, Italy.ORCID 0000-0002-9145-5400
Graziano GrugniDivision of Auxology, Istituto Auxologico Italiano, IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), 28824 Piancavallo-Verbania, Italy.ORCID 0000-0003-4708-2544
Gianluca CastelnuovoPsychology Research Laboratory, Istituto Auxologico Italiano, IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), 28824 Piancavallo-Verbania, Italy.ORCID 0000-0003-2633-9822
Alessandro SartorioExperimental Laboratory for Auxo-Endocrinological Research, Istituto Auxologico Italiano, IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), 28824 Piancavallo-Verbania, Italy.ORCID 0000-0002-9620-4133

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThis study aimed to evaluate quality of life in children and adolescents with normal variants of short stature compared to age- and sex-matched individuals with normal stature and to assess the agreement between children/adolescents-reported and parent-reported outcomes.

methodsA total of 65 child-parent dyads were enrolled, including 29 children and adolescents with short stature (15 males, 14 females; mean age: 11.2 + 2.0 years; mean height standard deviation score, HSDS: -2.10 + 0.57) and 36 children and adolescents with normal stature (19 males, 17 females; mean age: 11.3 + 1.93 years; mean HSDS: 0.56 + 0.78). Quality of life was assessed using the Quality of Life in Short Stature Youth (QoLISSY) questionnaire. Statistical analyses included independent samples

resultsAmong short-statured children and adolescents, no significant correlations were found between HSDS and all domains of quality of life. Short-statured children and adolescents exhibited significantly lower QoL across all domains compared to their normal-statured peers. Coping was higher in children and adolescents with short stature compared to their peers of normal stature. Similarly, parents of short-statured children and adolescents perceived a lower QoL for their sons and daughters and reported greater concern about the future and a more perceived personal impact than parents of normal-statured children and adolescents. No statistically significant differences were found between sons/daughters and parent reports, indicating a relatively high level of agreement in quality of life (QoL) perceptions.

conclusionsThese findings underscore the psychosocial impact of short stature and highlight the importance of incorporating both child and parent perspectives in the clinical assessment.

Indexed as

child/adolescent reportconstitutional growth delayfamilial short statureparent reportQoLISSYquality of lifeshort stature

Identifiers

PMID40941564
PMCPMC12428077

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