ArticleAnimals : an open access journal from MDPI2025
Evaluation of the Short-Term Effects of Mirtazapine on Appetite Stimulants in Dogs: A Retrospective Study and a Placebo-Controlled Trial.
Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anorexia and hyporexia are common clinical signs in dogs with acute or chronic illnesses, often requiring targeted nutritional interventions. Mirtazapine, an orexigenic drug widely used in cats, has limited evidence supporting its use in dogs. This study evaluated mirtazapine's efficacy as an appetite stimulant in dogs using a two-part approach: (1) a retrospective analysis of 107 clinical cases comparing dogs that received mirtazapine to untreated controls; and (2) a prospective, placebo-controlled, double-blind crossover trial involving 25 dogs. In the retrospective analysis, dogs treated with mirtazapine were significantly more likely to resume voluntary food intake (OR = 3.06) and had less weight loss compared to controls. In the prospective trial, mirtazapine significantly increased food acceptance on the first day (100% vs. 63.6%,
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.