ArticleFoods (Basel, Switzerland)2025
Development of Conjugated Linoleic Acid Nanostructured Lipid Carriers and Their Synergistic Efficacy with Curcumin.
Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Development and Optimization of Beeswax-Coriander Essential Oil-Based Nanostructured Lipid Carriers for Encapsulation of Anthocyanin-Rich Barberry Extract.Foods (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Curcumin has good anti-cancer and antioxidant properties. However, the poor water solubility and low bioavailability limit its application in food products. This study constructed a nanostructured lipid carrier (Cur-CLA-NLC) encapsulating curcumin using conjugated linoleic acid (CLA) as the liquid lipid and stearic acid as the solid lipid. Cur-CLA-NLC exhibits significantly enhanced bioaccessibility, antioxidant activity, and cytocompatibility. CLA, as a liquid lipid in Cur-CLA-NLC, has a dual role as a structural stabilizer and bioactive agent, and synergistically enhances antioxidant activity with curcumin. In vitro simulated digestion studies showed that the bioaccessibility of curcumin in Cur-CLA-NLC (85.7%) was much higher than that in the pure curcumin (11.7%) and curcumin lipid mixtures (9.3%). In addition, the Cur-CLA-NLC system showed anti-lipid peroxidation ability and good biocompatibility. Therefore, CLA-NLC can serve as a potential delivery system for enhancing health benefits via functional foods.
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Registered trials
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