Evidence map›Paper›PMID 40941189›Full record

ArticleFoods (Basel, Switzerland)2025

The Distinction of Chemical Profiles of Mountainous Forest Cultivated Ginseng and Garden Ginseng Based on Calcium Oxalate Crystals, Organic Acids, and Ginsenosides.

Xiaotong Zhang, Xiaoku Ran, Yidan Xi, Deqiang Dou

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Xiaotong ZhangCollege of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China.ORCID 0009-0006-1413-4247
Xiaoku RanCollege of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China.ORCID 0000-0003-2950-8898
Yidan XiCollege of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China.
Deqiang DouCollege of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China.ORCID 0000-0003-0571-3416

Funding

National Natural Science Foundation of China 82073985
6 · The paper itself

Abstract

This study aims to further analyze the chemical characteristics of mountainous forest cultivated ginseng (MFCG) and garden ginseng (GG), concerning their calcium oxalate crystals, organic acids, and ginsenosides. The results demonstrate that MFCG had higher levels of non-free oxalate, calcium oxalate crystals, and most ginsenosides, while GG had higher fumaric acid/total organic acids. The content of non-free oxalate and calcium oxalate crystals in rhizome was the highest, showing a positive correlation with the growth years (5-20 years). In most cases, in MFCG, non-free oxalic acid ≥ 0.8%, calcium oxalate ≥ 160/mg, fumaric acid/total organic acids < 9%, Rb1 ≥ 6 mg/g, PPD/PPT was close to 2, and Rb1/Ro ≥ 2.5, while in GG, non-free oxalic acid < 0.8%, calcium oxalate ≤ 60/mg, fumaric acid/total organic acids ≥ 9%, Rb1 < 6 mg/g, PPD/PPT was close to 1, and Rb1/Ro < 2.5. These results can be used as the basis for distinguishing between GG and MFCG. Chemometric analysis of non-free oxalate, calcium oxalate crystals, and ginsenosides could distinguish MFCG from GG. Chemometric analysis of succinate, citrate, and malonic acids could mostly differentiate MFCG of over 15 years from that of less than 12 years. As far as we know, the present study is the first to determine the difference in the ratio of ginsenosides (Rb1/Ro, PPD/PPT) and the ratio of organic acids, which provides an innovative method for the distinction between the two and a scientific basis for effective quality control of MFCG.

Indexed as

chemometric analysisGC/TQginsenosideHPLCmountainous forest cultivated ginsengorganic acidoxalic acid

Identifiers

PMID40941189
PMCPMC12427741

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.