Evidence map›Paper›PMID 40941118›Full record

ArticleFoods (Basel, Switzerland)2025

Green Synthesis of Selenium Nanoparticles by Grape Seed Extract Synergized with Ascorbic Acid: Preparation Optimization, Structural Characterization, and Functional Activity.

Hua Cheng, Li Wang, Shuqing Jia, Lu Wang, Shuiyuan Cheng, Yingtang Lu, Linling Li

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hua ChengSchool of Modern Industry for Selenium Science and Engineering, Wuhan Polytechnic University, Wuhan 430048, China.ORCID 0000-0003-4686-0404
Li WangSchool of Modern Industry for Selenium Science and Engineering, Wuhan Polytechnic University, Wuhan 430048, China.
Shuqing JiaSchool of Modern Industry for Selenium Science and Engineering, Wuhan Polytechnic University, Wuhan 430048, China.
Lu WangSchool of Modern Industry for Selenium Science and Engineering, Wuhan Polytechnic University, Wuhan 430048, China.
Shuiyuan ChengNational R&D Center for Se-Rich Agricultural Products Processing, Wuhan Polytechnic University, Wuhan 430023, China.
Yingtang LuSchool of Modern Industry for Selenium Science and Engineering, Wuhan Polytechnic University, Wuhan 430048, China.
Linling LiSchool of Modern Industry for Selenium Science and Engineering, Wuhan Polytechnic University, Wuhan 430048, China.

Funding

the Discipline Construction Project of Wuhan Polytechnic University 315-01003009the Science and Technology Major Program of Hubei Province 2024BBA002
6 · The paper itself

Abstract

Selenium nanoparticles (SeNPs) have broad application prospects in food preservation and drug development. In this study, grape seed extract (GSE) was used as a natural reducing agent and stabilizer, combined with ascorbic acid (Vc) for the green synthesis of SeNPs (GSE-SeNPs). The preparation process and structural stability were systematically optimized. Response surface methodology (RSM) was employed to optimize the concentrations of Vc and GSE, reaction time, and reaction temperature, aiming to screen out the optimal synthesis conditions with small particle size, good dispersibility, and the smallest PDI value. The results showed that the average particle size of GSE-SeNPs was 74.86 ± 6.07 nm, the PDI was 0.159 ± 0.028, and the Zeta potential was -30.42 ± 0.54 mV, indicating good stability. Characterization results revealed that GSE participated in the reduction and stabilization of SeNPs through electrostatic interactions and hydrogen bonds, forming spherical nanoparticles with a dense structure and good surface organic coating. In addition, GSE-SeNPs exhibited excellent DPPH free radical scavenging ability and antibacterial activity against

Indexed as

antibacterialantioxidantgrape seed extractresponse surface methodologyselenium nanoparticles

Identifiers

PMID40941118
PMCPMC12427814

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.