Evidence map›Paper›PMID 40941093›Full record

ReviewFoods (Basel, Switzerland)2025

Food-Grade Liposome-Loaded Delivery Systems: Current Trends and Future Perspectives.

Erkan Mankan, Canan Yagmur Karakas, Oznur Saroglu, Mondher Mzoughi, Osman Sagdic, Ayse Karadag

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Liposomal Formulation of Bioactive Substances fromInternational journal of molecular sciences · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Erkan MankanFood Engineering Department, Chemical, and Metallurgical Engineering Faculty, Yildiz Technical University, 34210 Istanbul, Türkiye.ORCID 0000-0001-5889-0083
Canan Yagmur KarakasFood Engineering Department, Chemical, and Metallurgical Engineering Faculty, Yildiz Technical University, 34210 Istanbul, Türkiye.ORCID 0000-0002-9653-5557
Oznur SarogluFood Engineering Department, Chemical, and Metallurgical Engineering Faculty, Yildiz Technical University, 34210 Istanbul, Türkiye.ORCID 0000-0002-4089-4008
Mondher MzoughiTrustlife Labs Drug Research & Development Center, 34774 Istanbul, Türkiye.ORCID 0000-0001-7368-8385
Osman SagdicFood Engineering Department, Chemical, and Metallurgical Engineering Faculty, Yildiz Technical University, 34210 Istanbul, Türkiye.ORCID 0000-0002-2063-1462
Ayse KaradagFood Engineering Department, Chemical, and Metallurgical Engineering Faculty, Yildiz Technical University, 34210 Istanbul, Türkiye.ORCID 0000-0001-8615-7321

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liposomes have emerged as versatile carriers in the food industry due to their amphiphilic structure, biocompatibility, and ability to encapsulate both hydrophilic and lipophilic bioactive compounds. They offer promising benefits by enhancing the solubility and bioavailability of food ingredients such as vitamins, polyphenols, carotenoids, peptides, and omega-3 fatty acids. However, liposomes in aqueous form often suffer from poor stability, leakage of encapsulated compounds, and sensitivity to environmental conditions. To address these challenges, hybrid delivery systems have been developed by incorporating liposomes into various solid or semi-solid encapsulation matrices such as nanofibers, particles, cast films, hydrogels, and emulsions. These combinations can offer synergistic advantages, including improved structural integrity, enhanced protection during processing and storage, extended-release profiles under digestive conditions, and versatile applicability across different applications. This review comprehensively discusses liposome structure, preparation methods, and their incorporation into various encapsulation matrices, focusing exclusively on food-grade ingredients. It highlights recent advancements in hybrid liposome-based systems tailored for food applications, with an emphasis on their functional performance and delivery efficiency. Overall, these hybrid systems hold great promise for developing next-generation functional foods with improved health benefits and shelf stability.

Indexed as

encapsulationfood-grade ingredientshealth-oriented foodnutraceuticals

Identifiers

PMID40941093
PMCPMC12428440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.