Evidence map›Paper›PMID 40941077›Full record

ArticleFoods (Basel, Switzerland)2025

Sea Cucumber Polysaccharides Promote Gut-Liver Axis Health by Modulating Microbiota, Metabolism, and Gene Expression in Mice.

Xue Sang, Zhuobin Xing, Boqian Zhou, Yiting Wang, Xin Guan, Fuyi Wang, Ying Li, Qiancheng Zhao, Zhibo Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xue SangCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China.ORCID 0000-0002-6472-5508
Zhuobin XingCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China.
Boqian ZhouCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China.
Yiting WangCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China.
Xin GuanCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China.
Fuyi WangCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China.
Ying LiCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China.ORCID 0000-0001-7138-7060
Qiancheng ZhaoCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China.
Zhibo LiCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China.

Funding

Key Science and Technology Program of Liaoning Province 2024JH2/102400002Liaoning Provincial Natural Science Foundation Program Project 2024JH2/102600074Liaoning Provincial Natural Science Foundation Program Project 2024-MSLH-049National Natural Science Foundation of China 32302093
6 · The paper itself

Abstract

This study investigated the beneficial effect of sea cucumber polysaccharides (SCP) on gut microbiota composition, metabolic profiles, and liver gene expression in mice. Using an integrative approach combining microbiome, metabolome, and transcriptome analyses, we demonstrated that SCP supplementation led to a marked rise in

Indexed as

arginine biosynthesismetabolomic analysisprebiotic effectssea cucumber polysaccharides

Identifiers

PMID40941077
PMCPMC12428159

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.