Evidence map›Paper›PMID 40941070›Full record

ArticleFoods (Basel, Switzerland)2025

In Vitro Digestion and Fecal Fermentation of Arecanut Polysaccharides: Effects on Gut Microbiota and Metabolites.

Xiaolong Ji, Ke Jiang, Yuqing Liu, Chenyu Zhao, Jun Du, Liang Chen, Zhigang Zhu, Xiaoqiong Li

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Food chemistry: X · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaolong JiCollege of Food and Bioengineering, Zhengzhou University of Light Industry, Zhengzhou 450001, China.ORCID 0000-0002-9043-603X
Ke JiangCollege of Food and Bioengineering, Zhengzhou University of Light Industry, Zhengzhou 450001, China.
Yuqing LiuCollege of Food and Bioengineering, Zhengzhou University of Light Industry, Zhengzhou 450001, China.
Chenyu ZhaoCollege of Food and Bioengineering, Zhengzhou University of Light Industry, Zhengzhou 450001, China.
Jun DuNutrilite Health Institute, Amway (Shanghai) Innovation & Science Co., Ltd., Shanghai 201203, China.
Liang ChenNutrilite Health Institute, Amway (Shanghai) Innovation & Science Co., Ltd., Shanghai 201203, China.ORCID 0000-0001-7434-4461
Zhigang ZhuNutrilite Health Institute, Amway (Shanghai) Innovation & Science Co., Ltd., Shanghai 201203, China.ORCID 0000-0001-5617-4825
Xiaoqiong LiInstitute of Food Science, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.

Funding

National Natural Science Foundation of China 32201969
6 · The paper itself

Abstract

Recent studies have increasingly emphasized the regulatory potential of plant-derived polysaccharides on gut microbial composition and metabolic function. Despite this growing interest, investigations focusing specifically on the simulated digestion and fermentation properties of arecanut polysaccharide (PAP1b) remain limited. In this work, we employed the standardized INFOGEST 2.0 protocol to mimic the oral, gastric, and intestinal digestion of PAP1b, followed by 48 h anaerobic fermentation using pooled human fecal samples from healthy adult donors. PAP1b treatment led to a progressive decrease in pH and a substantial elevation in SCFAs levels, notably acetic, propionic, and butyric acids. Simultaneously, PAP1b significantly promoted the growth of SCFA-producing microbial taxa, particularly members of the

Indexed as

arecanutgut microbiotain vitro fermentationmetabolitespolysaccharides

Identifiers

PMID40941070
PMCPMC12427847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.