ArticleCancers2025
Impact of Ultrasonographic Features Indicative of Malignancy on Tumor Advancement in Thyroid Cancer-A Single-Center Study.
Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Predictors of thyroid cancer in paediatric patients with thyroid nodules: A systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Pooled it
- Clinicopathological Significance of Ultrasound Risk Features and the Taller-Than-Wide Sign for Tumor Advancement in Differentiated Thyroid Cancer: A Single-Center Analysis.Cancer management and research · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundUltrasonography is frequently used preoperatively to assess thyroid nodules. Hypoechogenicity, microcalcifications, high vascularity, or irregular tumor shape suggest malignancy.
methodsThis is a retrospective analysis of 724 patients from 2008 to 2024 who underwent surgery for TC. Preoperative data, ultrasonographic findings, and histopathological results were collected. Ultrasonographic features indicative of possible malignancy included hypoechogenicity, microcalcifications, high vascularity, and irregular tumor shape. These were correlated with histopathologically seen extrathyroidal extension, capsular and vascular invasion, and lymph node metastasis.
resultsA statistically significant association was seen for each of the evaluated ultrasonographic features (
conclusionsUltrasonographic features predict the likelihood of histopathological extrathyroidal extension, capsular and vascular invasion, and lymph node metastasis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.