Evidence map›Paper›PMID 40940880›Full record

ReviewCancers2025

Failure to Rescue and Lung Resections for Lung Cancer: Measuring Quality from the Operation Room to the Intensive Care Unit.

Prokopis-Andreas Zotos, Vasiliki Androutsopoulou, Marco Scarci, Fabrizio Minervini, Ugo Cioffi, Andrew Xanthopoulos, Thanos Athanasiou, Dimitrios E Magouliotis

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Prokopis-Andreas ZotosDepartment of Cardiothoracic Surgery, University of Thessaly, Biopolis, 41110 Larissa, Greece.
Vasiliki AndroutsopoulouDepartment of Cardiothoracic Surgery, University of Thessaly, Biopolis, 41110 Larissa, Greece.ORCID 0009-0005-2445-0879
Marco ScarciDepartment of Cardiothoracic Surgery, Hammersmith Hospital, Imperial College Healthcare, National Health Service (NHS) Trust, London W12 0HS, UK.ORCID 0000-0002-4459-7721
Fabrizio MinerviniLuzern Kanton Hospital, 6000 Luzern, Switzerland.ORCID 0000-0003-3595-7307
Ugo CioffiDepartment of Surgery, University of Milan, 20122 Milan, Italy.ORCID 0000-0002-5321-5828
Andrew XanthopoulosDepartment of Cardiology, University of Thessaly, Biopolis, 41222 Larissa, Greece.
Thanos AthanasiouDepartment of Surgery and Cancer, Imperial College London, St Mary's Hospital, London W2 1NY, UK.
Dimitrios E MagouliotisDepartment of Cardiac Surgery Research, Lankenau Institute for Medical Research, Wynnewood, PA 19096, USA.ORCID 0000-0001-5417-6392

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Failure to rescue (FTR), defined as death following a potentially treatable postoperative complication, has emerged as a critical quality metric in thoracic surgery. In patients undergoing lung cancer resection, who are often at high risk due to comorbidities and limited pulmonary reserve, FTR significantly influences morbidity, mortality, recovery, and overall quality of life. This review explores the multifactorial nature of FTR in lung cancer surgery, highlighting key patient-related and system-level risk factors, such as surgical complexity, delayed complication recognition, inadequate escalation of care, and limited critical care resources. Existing models for patient rescue emphasize early detection and timely intervention, but often overlook the institutional and cultural changes required for sustainable improvement. Building on current evidence and integrating Kotter's eight-step change model, we propose a novel multidimensional roadmap to reduce FTR through proactive monitoring, structured escalation protocols, multidisciplinary coordination, and continuous learning. Finally, reducing FTR in lung cancer resection requires more than clinical responsiveness. This necessitates a systemic transformation that aligns frontline practice with institutional readiness and a culture of safety.

Indexed as

failure to rescueFTRlung cancerlung resectionmortalityqualitythoracic surgery

Identifiers

PMID40940880
PMCPMC12427398

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.