Evidence map›Paper›PMID 40940877›Full record

ArticleCancers2025

Multiplex Imaging Mass Cytometry Reveals Prognostic Immunosuppressive Subpopulations and Macrophage-Driven Metastasis in Osteosarcoma.

Benjamin B Gyau, Junyan Wang, Weiguo Wu, Brooks Scull, Angela M Major, Weidong Jin, Justin M M Cates, John Hicks, Tsz-Kwong Man

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Benjamin B GyauSection of Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0003-3871-8168
Junyan WangSection of Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
Weiguo WuSection of High Parameter Cytometry, Cytometry and Cell Sorting Core, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0009-0005-7981-350X
Brooks ScullSection of Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
Angela M MajorSection of Histological Research and Development, Department of Pathology, Texas Children's Hospital, Houston, TX 77030, USA.
Weidong JinSection of Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0009-0002-4573-6524
Justin M M CatesPathGroup Laboratories, Nashville, TN 37217, USA.
John HicksTexas Children's Cancer and Hematology Center, Houston, TX 77030, USA.
Tsz-Kwong ManSection of Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0001-5920-5746

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Suzanne AW Fuqua · 2007 to 2026
$73.9M
BD Biosciences Special Order LSRIIS10RR024574 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI LUMPKIN, ELLEN A · 2009 to 2009
$430k
Cancer Prevention and Research Institute of Texas RP200135NCI NIH HHS P30 CA125123NCRR NIH HHS S10 RR024574NIH HHS 1P30CA125123-23NIH HHS 1S10AR024574-23
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

imaging mass cytometryimmune-tumor crosstalkimmunosuppressive cellsM2 macrophagesmetastasismigrationMIP-1αosteosarcomaspatial analysistumor microenvironment

Identifiers

PMID40940877
PMCPMC12427482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.