Evidence map›Paper›PMID 40940823›Full record

ArticleCancers2025

Etiologies and Outcomes of Diabetic Ketoacidosis in Cancer Patients: A Retrospective Analysis.

Ayush Gandhi, Rebecca Jeun, Zhongya Wang, Sonya Khan, Conor Best, Victor Lavis, Sonali Thosani

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ayush GandhiDepartment of Hospital Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.ORCID 0009-0008-8508-152X
Rebecca JeunDepartment of Endocrinology, Diabetes and Nutrition Care, University of Louisville Health, Louisville, KY 40202, USA.ORCID 0000-0002-8305-5810
Zhongya WangDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.ORCID 0000-0002-3866-8052
Sonya KhanDepartment of Endocrine Neoplasia & Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Conor BestDepartment of Endocrine Neoplasia & Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Victor LavisDepartment of Endocrine Neoplasia & Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.ORCID 0000-0002-1422-4764
Sonali ThosaniDepartment of Endocrine Neoplasia & Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.ORCID 0000-0002-4149-3572

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Kathrin Milbury · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

BACKGROUND/

objectivesDiabetic ketoacidosis (DKA) is a life-threatening emergency resulting in significant morbidity and health care utilization. The most common cause of DKA in the general population is insulin nonadherence, but limited data exists on precipitating factors for DKA in cancer patients. In this study, we characterize the demographic and clinical characteristics of hospitalized patients with DKA at our comprehensive cancer center.

methodsThis single-center retrospective study evaluated 91 patients with 94 admissions for DKA at our institution between January 2019 and December 2021. Demographic, clinical, and biochemical data were obtained from a review of the electronic medical record. Patient characteristics were summarized using descriptive statistics for continuous variables and categorical variables.

resultsOf the 91 patients, 21% of patients (

conclusionsWe characterized the precipitating factors for DKA based on patients' underlying diabetes status. While insulin non-adherence was the most common cause in patients with known type 1 diabetes, drugs associated with cancer related treatments emerged most common precipitating factor for DKA in cancer patients with underlying type 2 diabetes or drug induced diabetes. A tailored approach with proactive counseling may be helpful in timely recognition and treatment of DKA in cancer patients.

Indexed as

cancer related hyperglycemiacancer treatment complicationdiabetic ketoacidosis (DKA)euglycemic DKAglucose monitoring in canceroncology endocrinologysteroid induced hyperglycemia

Identifiers

PMID40940823
PMCPMC12427185

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.