Evidence map›Paper›PMID 40940818›Full record

ArticleCancers2025

Paola Parente, Valentina Angerilli, Federica Grillo, Maria Raffaella Ambrosio, Federica Petrelli, Jessica Gasparello, Francesca Antoci, Emanuela Pilozzi, Stefania Scarpino, Flavia Adotti and 16 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Paola ParentePathology Unit, Fondazione IRCCS Ospedale Casa Sollievo Della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, Italy.ORCID 0000-0003-0591-6723
Valentina AngerilliSurgical Pathology Unit, Department of Medicine, University of Padua, Via Gabelli 60, 35121 Padua, Italy.
Federica GrilloAnatomic Pathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DICS), University of Genova, Via Balbi 5, 16026 Genova, Italy.ORCID 0000-0001-6477-3182
Maria Raffaella AmbrosioAzienda Ospedaliera Universitaria "SS. Annunziata", University of Calabria (UNICAL), Via Migliori 1, 87100 Cosenza, Italy.ORCID 0000-0002-1172-6902
Federica PetrelliUOC Anatomia Patologica, Azienda Toscana Nord Ovest, Via Cocchi, 56121 Pisa, Italy.
Jessica GasparelloSurgical Pathology Unit, Department of Medicine, University of Padua, Via Gabelli 60, 35121 Padua, Italy.
Francesca AntociSC Anatomia Patologica, Fondazione IRCCS Policlinico San Matteo, Via Carlo Forlanini 14, 27100 Pavia, Italy.
Emanuela PilozziDepartment of Clinical and Molecular Medicine, "Sapienza" University of Rome, UOC Anatomia Patologica Morfologia e Molecolare Azienda Ospedaliera-Universitaria Sant'Andrea, Via di Grottarossa 1035, 00189 Roma, Italy.ORCID 0000-0002-7110-9172
Stefania ScarpinoDepartment of Clinical and Molecular Medicine, "Sapienza" University of Rome, UOC Anatomia Patologica Morfologia e Molecolare Azienda Ospedaliera-Universitaria Sant'Andrea, Via di Grottarossa 1035, 00189 Roma, Italy.
Flavia AdottiDepartment of Experimental Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161 Rome, Italy.ORCID 0000-0002-9233-298X
Andrea AscioneDepartment of Experimental Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161 Rome, Italy.ORCID 0000-0002-4253-3193
Norman VecciaUOC Anatomia Patologica Azienda Ospedaliera San Camillo Forlanini, Circonvallazione Gianicolense 87, 00152 Roma, Italy.
Alessandro CaputoDepartment of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Via S. Allende 43, 84081 Baronissi, Italy.ORCID 0000-0001-5139-3869
Mariantonia GiobbeDepartment of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Via S. Allende 43, 84081 Baronissi, Italy.
Roberta GafàAnatomic Pathology Unit, Department of Translational Medicine, University of Ferrara, Azienda Ospedaliero-Universitaria S. Anna, Via Aldo Moro, 8, 44124 Ferrara, Italy.ORCID 0000-0002-3271-2198
Laura MelocchiPathology Unit, Fondazione Poliambulanza Instituto Ospedaliero, Via Leonida Bissolati 57, 25124 Brescia, Italy.ORCID 0000-0001-5161-6305
Laura GandolfiPathology Unit, Fondazione Poliambulanza Instituto Ospedaliero, Via Leonida Bissolati 57, 25124 Brescia, Italy.
Paola ParrellaLaboratory of Oncology Fondazione IRCCS Ospedale Casa Sollievo Della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, Italy.ORCID 0000-0001-6031-9636
Barbara PasculliLaboratory of Oncology Fondazione IRCCS Ospedale Casa Sollievo Della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, Italy.ORCID 0000-0002-3333-0255
Francesco VasuriPathology Unit, Santa Maria delle Croci Hospital, Ravenna, Viale Randi 5, 48121 Ravenna, Italy.ORCID 0000-0002-1145-6025
Maria Cristina MacciomeiUOC Anatomia Patologica Azienda Ospedaliera San Camillo Forlanini, Circonvallazione Gianicolense 87, 00152 Roma, Italy.ORCID 0000-0002-4199-5636
Alessandro VanoliSC Anatomia Patologica, Fondazione IRCCS Policlinico San Matteo, Via Carlo Forlanini 14, 27100 Pavia, Italy.ORCID 0000-0002-2976-7032
Luca SaragoniPathology Unit, Santa Maria delle Croci Hospital, Ravenna, Viale Randi 5, 48121 Ravenna, Italy.
Giovanni LanzaAnatomic Pathology Unit, Department of Translational Medicine, University of Ferrara, Azienda Ospedaliero-Universitaria S. Anna, Via Aldo Moro, 8, 44124 Ferrara, Italy.
Luca MastracciAnatomic Pathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DICS), University of Genova, Via Balbi 5, 16026 Genova, Italy.ORCID 0000-0003-0193-5281
Matteo FassanSurgical Pathology Unit, ULSS2 Marca Trevigiana, Piazzale Ospedale 1, 31100 Treviso, Italy.ORCID 0000-0001-6515-5482

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionColorectal cancer (CRC) is the third most frequent malignancy and the second cause of cancer-related death worldwide. CRC is characterized by morphologic and biological heterogeneity, and molecular profiling is required to select appropriate treatment in the metastatic setting. Mutations in MATERIALS AND

methodsWe retrospectively collected clinicopathological features and molecular profiles of CRCs in a multicenter cohort.

resultsA total of 2816 patients from 12 centers were included.

conclusionsRecent data have pinpointed the prognostic and predictive value of

Indexed as

biomarkerscolorectal adenocarcinomaGly12AspKRASmutational analysisp.G12D

Identifiers

PMID40940818
PMCPMC12427293

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.