Evidence map›Paper›PMID 40940780›Full record

ArticleCells2025

Deficiency of N1-Adenine Methyltransferase Aggravates RNA and Protein Aggregation.

Marion Alriquet, Roberto Arsiè, Giulia Calloni, Gian G Tartaglia, R Martin Vabulas

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Methyladenine as a regulator of biomolecular condensation.Frontiers in molecular biosciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marion AlriquetBuchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, 60438 Frankfurt am Main, Germany.
Roberto ArsièInstitute of Biochemistry, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.ORCID 0000-0002-7869-7624
Giulia CalloniBuchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, 60438 Frankfurt am Main, Germany.
Gian G TartagliaCentre for Human Technologies (CHT), RNA System Biology Lab, Istituto Italiano di Tecnologia, 16152 Genoa, Italy.
R Martin VabulasInstitute of Biochemistry, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.

Funding

Deutsche Forschungsgemeinschaft EXC115Else Kröner-Fresenius-Stiftung 2021_EKSE.137European Research Council StG-311522
6 · The paper itself

Abstract

RNA modifications regulate diverse aspects of transcripts' function and stability. Among these, N1-methyladenine (m

Indexed as

MethyltransferasesProtein AggregatesRNAAdenineAmyloidHEK293 CellsHumansMethylationRNA, MessengertRNA MethyltransferasesAdenineAmyloidMethyltransferasesProtein AggregatesRNARNA, MessengertRNA MethyltransferasesN1-methyladenineprotein aggregationRBPTRMT6/TRMT61A

Identifiers

PMID40940780
PMCPMC12428715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.