Evidence map›Paper›PMID 40940767›Full record

ArticleCells2025

Deciphering α-L-Fucosidase Activity Contribution in Human and Mouse: Tissue α-L-Fucosidase FUCA1 Meets Plasma α-L-Fucosidase FUCA2.

Hannah Bäumges, Svenja Jelinek, Heike Lange, Sandra Markmann, Emanuela Capriotti, Jan Anwar Häusser, Mai-Britt Ilse, Thomas Braulke, Torben Lübke

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hannah BäumgesDepartment of Chemistry, Biochemistry III, Bielefeld University, 33615 Bielefeld, Germany.
Svenja JelinekDepartment of Chemistry, Biochemistry III, Bielefeld University, 33615 Bielefeld, Germany.ORCID 0009-0006-5130-9878
Heike LangeDepartment of Chemistry, Biochemistry III, Bielefeld University, 33615 Bielefeld, Germany.
Sandra MarkmannInstitute of Osteology & Biomechanics, Cell Biology of Rare Diseases, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Emanuela CapriottiInstitute of Osteology & Biomechanics, Cell Biology of Rare Diseases, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Jan Anwar HäusserDepartment of Chemistry, Biochemistry III, Bielefeld University, 33615 Bielefeld, Germany.ORCID 0009-0006-9753-5248
Mai-Britt IlseDepartment of Chemistry, Biochemistry III, Bielefeld University, 33615 Bielefeld, Germany.
Thomas BraulkeInstitute of Osteology & Biomechanics, Cell Biology of Rare Diseases, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-2336-8532
Torben LübkeDepartment of Chemistry, Biochemistry III, Bielefeld University, 33615 Bielefeld, Germany.ORCID 0000-0002-3342-0090

Funding

Deutsche Forschungsgemeinschaft FOR2625 TP7
6 · The paper itself

Abstract

Fucose-containing glycoproteins and glycolipids broadly occur in humans as well as in many other species and are essential for a wide range of physiological processes, such as cell adhesion, fertilization, and tumor development. In humans, the cellular degradation of various fucosylated glycoconjugates depends on the

Indexed as

alpha-L-FucosidaseAnimalsFucoseHumansLysosomesMicealpha-L-FucosidaseFUCA1 protein, humanFucoseFUCA1FUCA2fucosidosislysosomal storage diseaselysosomesα-L-fucosidase 1α-L-fucosidase 2

Identifiers

PMID40940767
PMCPMC12427801

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.