ArticleCells2025
Profibrotic Molecules Are Reduced in CRISPR-Edited Emery-Dreifuss Muscular Dystrophy Fibroblasts.
Abstract read
In one paragraph
Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Emerin is necessary for microtubule-organizing center translocation to the nuclear envelope of muscle cells.Cell death & disease · 2026Article
- Cardiac Involvement in Emery-Dreifuss Muscular Dystrophy, from Arrhythmias to Heart Failure and Sudden Death: A Contemporary Review.Journal of clinical medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
29 authors.
Eleonora CattinDepartment of Life Sciences, University of Modena and Reggio Emilia, 41121 Modena, Italy.ORCID 0009-0007-3737-2181
Elisa SchenaCNR Institute of Molecular Genetics "Luigi Luca Cavalli-Sforza", Unit of Bologna, 40136 Bologna, Italy.ORCID 0000-0001-5960-4157
Elisabetta MattioliCNR Institute of Molecular Genetics "Luigi Luca Cavalli-Sforza", Unit of Bologna, 40136 Bologna, Italy.ORCID 0000-0002-1395-1927
Stefania MarcuzzoNeurology 4-Neuroimmunology and Neuromuscular Diseases, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy.ORCID 0000-0001-6893-6372
Silvia BonannoNeurology 4-Neuroimmunology and Neuromuscular Diseases, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy.ORCID 0000-0002-8823-6821
Paola CavalcanteNeurology 4-Neuroimmunology and Neuromuscular Diseases, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy.ORCID 0000-0002-1497-1524
Federico CorradiDepartment of Life Sciences, University of Modena and Reggio Emilia, 41121 Modena, Italy.ORCID 0009-0006-4926-0411
Daniela BenatiDepartment of Life Sciences, University of Modena and Reggio Emilia, 41121 Modena, Italy.ORCID 0000-0002-6599-7193
Giorgia FarinazzoNeurology 4-Neuroimmunology and Neuromuscular Diseases, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy.ORCID 0009-0002-4177-8647
Marco CattaneoNeurology III-Neuroalgology Unit, IRCCS "C. Besta" Neurologic Institute, 20133 Milan, Italy.
Veronica De SanctisDepartment of Cellular, Computational and Integrative Biomedicine-CIBIO LaBSSAH, University of Trento, 38122 Trento, Italy.ORCID 0000-0002-9791-5316
Roberto BertorelliDepartment of Cellular, Computational and Integrative Biomedicine-CIBIO LaBSSAH, University of Trento, 38122 Trento, Italy.ORCID 0000-0002-2541-5419
Lorenzo MaggiNeurology 4-Neuroimmunology and Neuromuscular Diseases, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy.ORCID 0000-0002-0932-5173
Melania GiannottaIRCCS Istituto delle Scienze Neurologiche di Bologna, 40124 Bologna, Italy.
Antonella PiniIRCCS Istituto delle Scienze Neurologiche di Bologna, 40124 Bologna, Italy.ORCID 0000-0003-3603-5478
Gaetano VattemiDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37124 Verona, Italy.ORCID 0000-0003-3412-8339
Denise CassandriniDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37124 Verona, Italy.
Marco CavalloShoulder & Elbow Surgery Department, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0002-7645-4370
Cristina ManferdiniIRCCS Istituto Ortopedico Rizzoli, Laboratorio di Immunoreumatologia e Rigenerazione Tissutale, 40136 Bologna, Italy.ORCID 0000-0002-6648-6061
Gina LisignoliIRCCS Istituto Ortopedico Rizzoli, Laboratorio di Immunoreumatologia e Rigenerazione Tissutale, 40136 Bologna, Italy.ORCID 0000-0003-2837-9967
Beatrice FontanaDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126 Bologna, Italy.ORCID 0009-0006-8578-3690
Ilaria PaceDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126 Bologna, Italy.
Claudio BrunoDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genova, 16132 Genova, Italy.
Roberta RoncaratiCNR Institute of Molecular Genetics "Luigi Luca Cavalli-Sforza", Unit of Bologna, 40136 Bologna, Italy.ORCID 0000-0002-2371-3316
Chiara FiorilloDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genova, 16132 Genova, Italy.
Manuela FerracinDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-1595-6887
Eric C SchirmerInstitute of Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, UK.ORCID 0000-0003-2635-1338
Alessandra RecchiaDepartment of Life Sciences, University of Modena and Reggio Emilia, 41121 Modena, Italy.ORCID 0000-0002-3467-1094
Giovanna LattanziCNR Institute of Molecular Genetics "Luigi Luca Cavalli-Sforza", Unit of Bologna, 40136 Bologna, Italy.ORCID 0000-0002-7103-8722
Funding
AIFA TREAT-LMNA 2019-004426-24Associazione Alessandra Proietti OdV CUP B33C22001640007Associazione Italiana DIstrofia Muscolare di Emery-Dreifuss - AIDMED CUP B33C22001640007EU-funded PNRR ECOSISTER Project. cod. ECS_00000033-CUP B89I22000650001EU-funded PNRR ECOSISTER project ECS_00000033 - CUP E93C22001100001Ministero della Salute T3-AN-03 CUP: B53C22002520006 REGINAMinistero dell'università e della ricerca 20223WFJJ3The Italian Ministry of Health RRC
Abstract
Emery-Dreifuss muscular dystrophy (EDMD) is caused by mutations in
Indexed as
CRISPR-Cas SystemsFibroblastsGene EditingMuscular Dystrophy, Emery-DreifussFibrosisHumansLamin Type AMicroRNAsMutationMyofibroblastsLamin Type AMicroRNAsCRISPR/Cas gene editingEDMDemerinfibrosislaminopathiesmiRNA profiling
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.