Evidence map›Paper›PMID 40940688›Full record

ArticleThe Australian and New Zealand journal of psychiatry2025

Addressing the unmet needs of bipolar disorder in Australia and beyond.

Sue M Cotton, Melissa Hasty, Philip Mitchell, Greg Murray, Ian B Hickie, Patrick D McGorry, Ken Walder, Olivia M Dean, Cathy Mihalopoulos, Alison R Yung and 16 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Australian and New Zealand journal of psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Sue M CottonSchool of Psychological Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC, Australia.ORCID 0000-0002-9386-8348
Melissa HastySchool of Psychological Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC, Australia.ORCID 0009-0000-9040-7602
Philip MitchellDiscipline of Psychiatry and Mental Health, Faculty of Medicine and Health, University of New South Wales, Randwick, NSW, Australia.ORCID 0000-0002-7954-5235
Greg MurrayCentre for Mental Health and Brain Sciences, School of Health Sciences, Swinburne University, Melbourne, VIC, Australia.
Ian B HickieBrain and Mind Centre, The University of Sydney, Camperdown, NSW, Australia.ORCID 0000-0001-8832-9895
Patrick D McGorryCentre for Youth Mental Health, The University of Melbourne, Parkville, VIC, Australia.ORCID 0000-0002-3789-6168
Ken WalderInstitute for Mental and Physical Health and Clinical Translation, School of Medicine, Deakin University, Geelong, VIC, Australia.ORCID 0000-0002-6758-4763
Olivia M DeanInstitute for Mental and Physical Health and Clinical Translation, School of Medicine, Deakin University, Geelong, VIC, Australia.
Cathy MihalopoulosMonash University Health Economics Group, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
Alison R YungInstitute for Mental and Physical Health and Clinical Translation, School of Medicine, Deakin University, Geelong, VIC, Australia.ORCID 0000-0002-0401-9791
Tamsyn E Van RheenenCentre for Mental Health and Brain Sciences, School of Health Sciences, Swinburne University, Melbourne, VIC, Australia.ORCID 0000-0003-3339-6665
Andrew A NierenbergHarvard Medical School, Boston, MA, USA.
Jan ScottAcademic Psychiatry, Institute of Neuroscience, Newcastle University, Newcastle, UK.ORCID 0000-0002-7203-8601
Lana J WilliamsInstitute for Mental and Physical Health and Clinical Translation, School of Medicine, Deakin University, Geelong, VIC, Australia.ORCID 0000-0002-1377-1272
Lesley BerkInstitute for Mental and Physical Health and Clinical Translation, School of Medicine, Deakin University, Geelong, VIC, Australia.ORCID 0000-0002-3677-7503
Christopher G DaveyDepartment of Psychiatry, The University of Melbourne, Parkville, VIC, Australia.ORCID 0000-0003-1431-3852
Jacob J CrouseBrain and Mind Centre, The University of Sydney, Camperdown, NSW, Australia.ORCID 0000-0002-3805-2936
Elizabeth ScottBrain and Mind Centre, The University of Sydney, Camperdown, NSW, Australia.ORCID 0000-0003-3907-0324
Frank IorfinoBrain and Mind Centre, The University of Sydney, Camperdown, NSW, Australia.ORCID 0000-0003-1109-0972
Kate FiliaCentre for Youth Mental Health, The University of Melbourne, Parkville, VIC, Australia.ORCID 0000-0001-6581-5890
Mary Lou ChattertonMonash University Health Economics Group, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.ORCID 0000-0003-4902-9448
Craig MacneilOrygen Ltd, Parkville, VIC, Australia.ORCID 0000-0002-7075-1593
Tania PerichSchool of Psychology, Western Sydney University, Sydney, NSW, Australia.ORCID 0000-0003-2843-8939
Emma MortonSchool of Psychological Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC, Australia.ORCID 0000-0001-6179-1983
Aswin RatheeshCentre for Youth Mental Health, The University of Melbourne, Parkville, VIC, Australia.ORCID 0000-0002-8029-9422
Michael BerkOrygen Ltd, Parkville, VIC, Australia.ORCID 0000-0002-5554-6946

Funding

Al and Val Rosenstrauss Fellowship from the Rebecca L Cooper Medical Research Foundation. F.I. is supported by an NHMRC EL1 Investigator Grant GNT2018157NHMRC CRE grant GNT 2015747NHMRC Emerging Leadership Investigator Grant GNT1174060NHMRC Emerging Leadership Investigator Grant GNT2008196NHMRC Leadership 3 Investigator grant GNT2016346NHMRC Leadership 3 Investigator grant GNT2017131NHMRC Leadership 3 Investigator Grant GNT1177991
6 · The paper itself

Abstract

People impacted by bipolar disorder are confronted by many unmet needs that contribute to the overall burden associated with the disorder. We do not have a good understanding of the underlying pathology of bipolar disorder, so we do not have biomarkers to accurately identify those who are at risk of developing the disorder. Delayed diagnosis is the norm, and it can take a decade or more for an individual to receive a diagnosis and to start appropriate treatment. We have evidence-based treatments such as lithium and psychosocial therapies; however, their availability and use are limited. We need a consolidated approach to advance indicated prevention and early intervention for bipolar disorder. In this viewpoint article, we describe these barriers in detail as well as introduce international and national work that is being done to progress the field. At the national level, we introduce the National Health and Medical Research Council Centre for Research Excellence in Bipolar Disorder. The Centre for Research Excellence in Bipolar Disorder comprises a multidisciplinary team of experts from Australia and internationally who are working together to develop a better understanding of opportunities for indicated prevention and early intervention as well as to improve interventions for those impacted by the disorder. Here we describe our research framework, stakeholder engagement activities and strategies for workforce development and capacity building. Ultimately by working together we will attempt to address many of issues faced by individuals impacted by bipolar disorder.

Indexed as

Bipolar DisorderHealth Services Needs and DemandAustraliaHumansBipolar disordercapacity buildingdepressionearly interventionmaniamental healthpsychiatrystakeholder engagementtreatment

Identifiers

PMID40940688
PMCPMC12569142

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.