ArticleBMC infectious diseases2025
Epidemiological analysis of syphilis trends, disparities, and public health implications in the United States, 2018-2022.
Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Syphilis Co-Infection Among People Living with HIV in Romania: Epidemiological and Clinical Characteristics in a Single-Center Retrospective Study.Pathogens (Basel, Switzerland) · 2026Article
- Health literacy and syphilis knowledge: findings from a national survey of U.S. women of reproductive age.BMC public health · 2025Article
- Research progress on the mechanisms of neurosyphilis' impact on cognitive function, early identification, and prevention strategies.Frontiers in neurology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Syphilis has experienced a marked resurgence in the United States since 2018, with incidence rates reaching levels not observed since the pre-antibiotic era. Despite growing awareness among healthcare professionals and public health authorities, a comprehensive epidemiological analysis of the populations most affected during this period remains limited. This study examines the rise in syphilis cases from 2018 to 2022 using surveillance data from the Centers for Disease Control and Prevention (CDC). We evaluate trends across key demographic variables including race, sexual behavior, geographic distribution, substance use, and sex of sexual partner. Additionally, we assess the role of socioeconomic determinants that may impede access to prevention, diagnosis, and treatment. By identifying disproportionately affected populations, this research aims to inform targeted public health interventions and guide evidence-based policy responses to mitigate the ongoing syphilis epidemic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.