ArticleScientific reports2025
Feasibility of high-resolution DWI of the healthy dental pulp in human using a hybrid TGSE BLADE sequence.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Clinical evaluation of the human dental pulp is limited to imprecise, subjective methods, necessitating the development of an accurate and objective diagnostic parameter. Diffusion-weighted imaging (DWI) could address this gap; however, no in vivo data are available. To illustrate the feasibility of DWI imaging of the human pulp and to investigate physiological patterns. A turbo gradient spin echo (TGSE) BLADE diffusion MRI sequence was optimized for dental pulp imaging in three volunteers, defining an optimal b-value range and assessing intraindividual fluctuations at 3 T. Apparent diffusion coefficient (ADC) values were calculated in 18 participants using the 2-point and 7-point methods in 329 healthy teeth, analyzing data according to tooth and jaw type. Statistical analysis was performed using Kruskal-Wallis, Wilcoxon signed-rank-test, and one-way ANOVA. Mean pulp ADCs (± SD) for the 2-/7-point methods were 1.219 ± 0.340 / 1.242 ± 0.297 × 10
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