Evidence map›Paper›PMID 40940166›Full record

ArticleInternational journal of spine surgery2025

From Incision to Prescription: Unraveling Pain and Opioid Use in Adult Spinal Deformity Surgery.

Samantha Schimmel, Molly Monsour, Kiana Yeganeh, Schahin Salmanian, Chloe Chose, Anjali Pradhan, Diego T Soto-Rubio, Cesar Carballo Cuello, Jay I Kumar, Puya Alikhani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of spine surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Samantha SchimmelUniversity of South Florida Morsani College of Medicine, Tampa, FL, USA.
Molly MonsourUniversity of South Florida Morsani College of Medicine, Tampa, FL, USA.
Kiana YeganehUniversity of South Florida Morsani College of Medicine, Tampa, FL, USA.
Schahin SalmanianUniversity of South Florida Morsani College of Medicine, Tampa, FL, USA.
Chloe ChoseUniversity of South Florida Morsani College of Medicine, Tampa, FL, USA.
Anjali PradhanDepartment of Neurosurgery and Brain Repair, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Diego T Soto-RubioDepartment of Neurosurgery and Brain Repair, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Cesar Carballo CuelloDepartment of Neurosurgery and Brain Repair, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Jay I KumarDepartment of Neurosurgery and Brain Repair, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Puya AlikhaniDepartment of Neurosurgery and Brain Repair, University of South Florida Morsani College of Medicine, Tampa, FL, USA palikhan@usf.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdult spinal deformity (ASD) surgery often involves extensive spinal realignment to restore spinopelvic parameters and functional alignment. Unfortunately, patients frequently experience significant postoperative pain, often leading to prolonged opioid use. This study investigates patient- and surgery-related factors associated with opioid use and pain following ASD surgery.

methodsWe conducted a retrospective review of ASD cases performed at our institution between 2016 and 2023. All patients underwent multilevel spinal fusion for correction of scoliosis and/or kyphosis.

resultsOf the 264 patients, 231 (88%) required opioids postoperatively, and 22.4% remained on opioids at 12 months. Preoperative opioid use (

conclusionThis study highlights several key risk factors for prolonged opioid dependence and elevated postoperative pain in ASD surgery, including preoperative narcotic use, postoperative PI < 55°, revision surgery for mechanical complications, and specific osteotomy techniques. The protective effect of IDO in reducing pain and opioid duration is most likely due to more harmonious correction of lumbar lordosis and an improvement in lumbar lordosis-PI mismatch. CLINICAL RELEVANCE: These findings underscore the importance of preoperative optimization, opioid-sparing pain management strategies, and enhanced recovery pathways to mitigate long-term opioid reliance and improve patient outcomes. LEVEL OF EVIDENCE: 3:

Indexed as

adult spinal deformity surgerymechanical complicationsopioidsosteotomy techniquespostoperative pain

Identifiers

PMID40940166
PMCPMC12800656

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.