Evidence map›Paper›PMID 40940114›Full record

ArticleJACC. Case reports2025

Utilizing Mixed Reality Technology to Facilitate Coronary Chronic Total Occlusion Antegrade Wiring: A Pilot Study.

Cheng-Wei Lien, Hao-Yun Lo, Wen-Jeng Lee, Li-Pin Chen, Chih-Cheng Wu, Hsien-Li Kao, Mu-Yang Hsieh, Ching-Ting Tan

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cheng-Wei LienCardiovascular Division, Department of Internal Medicine, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu, Taiwan; National Taiwan University Hospital, Hsin-Chu Branch, Cardiovascular Center, Hsinchu, Taiwan.
Hao-Yun LoCardiovascular Division, Department of Internal Medicine, Shin Kong Wu Ho Su Memorial Hospital, Taipei, Taiwan.
Wen-Jeng LeeDepartment of Radiology, National Taiwan University Hospital, Taipei, Taiwan.
Li-Pin ChenDepartment of Radiology, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu, Taiwan.
Chih-Cheng WuCardiovascular Division, Department of Internal Medicine, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu, Taiwan; National Taiwan University Hospital, Hsin-Chu Branch, Cardiovascular Center, Hsinchu, Taiwan.
Hsien-Li KaoCardiovascular Division, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Mu-Yang HsiehCardiovascular Division, Department of Internal Medicine, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu, Taiwan; National Taiwan University Hospital, Hsin-Chu Branch, Cardiovascular Center, Hsinchu, Taiwan; National Taiwan University, College of Medicine, Taipei, Taiwan.
Ching-Ting TanThe Intelligent Healthcare Innovation Center, National Taiwan University Hospital, Hsin-Chu Branch, Taipei, Taiwan. Electronic address: g03580@hch.gov.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPercutaneous coronary intervention (PCI) for chronic total occlusion (CTO) is technically demanding. This pilot study evaluated the feasibility and safety of mixed reality technology to assist antegrade wiring during CTO PCI.

methodsWe developed a workflow using HoloLens mixed reality goggles to assist antegrade wiring by integrating coronary computed tomography angiography images. Two strategies-overlay and side-by-side display-were tested. Feasibility and safety were assessed using semi-qualitative scoring and confirmation of intraluminal wire position by intravascular ultrasound (IVUS).

resultsFive patients underwent CTO PCI with mixed reality guidance during the antegrade wiring phase, all achieving procedural success. Antegrade wiring was successful in 4 cases; 1 case required retrograde wiring. Operator-reported feasibility and safety scores were high, and IVUS confirmed intraluminal wire passage in 4 cases.

conclusionsThis pilot study reports initial experience from the first 5 cases of mixed reality-guided CTO PCI. The technology enhanced operator confidence and safety in achieving intraluminal wiring.

Indexed as

coronary chronic total occlusionmixed realitypercutaneous coronary intervention

Identifiers

PMID40940114
PMCPMC12789722

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.