Evidence map›Paper›PMID 40940015›Full record

ArticleOtology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology2025

Symptom and Handicap Severity in Subacute Dizzy Patients: The Role of Gaze Position Error in Video Head Impulses.

Athanasia Korda, Thomas Wyss, Ewa Zamaro, Efterpi Michailidou, Tom Gawliczek, Franca Wagner, Marco D Caversaccio, Georgios Mantokoudis

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Article in Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Athanasia KordaDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, University Hospital Bern and University of Bern.
Thomas WyssDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, University Hospital Bern and University of Bern.
Ewa ZamaroDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, University Hospital Bern and University of Bern.
Efterpi MichailidouDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, University Hospital Bern and University of Bern.
Tom GawliczekDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, University Hospital Bern and University of Bern.
Franca WagnerUniversity Institute of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital Bern and University of Bern, Bern, Switzerland.
Marco D CaversaccioDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, University Hospital Bern and University of Bern.
Georgios MantokoudisDepartment of Otorhinolaryngology, Head and Neck Surgery, Inselspital, University Hospital Bern and University of Bern.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to investigate the significance of gaze position error (GPE) after rapid head movements in the recovery of symptoms among patients with acute unilateral vestibulopathy (AUVP).

methodsWe studied 26 patients with AUVP and a control group of 48 healthy subjects. All patients received a video head impulse test (vHIT) during the acute stage and a follow-up vHIT 30 days after symptoms onset. Additionally, they completed a Dizziness Handicap Inventory (DHI) questionnaire.

resultsBased on our normative data, we found a cutoff amplitude of 4 degrees for abnormal GPE. Mean DHI score was 26.7 (±28.9 SD). Seventeen patients had a mild, four had a moderate, and five a severe dizziness handicap. DHI was highly correlated with GPE (adjusted R2 = 0.446) and with the vestibulo-ocular reflex (VOR) gain (adjusted R2 = 0.272). Although age and gender were not significantly associated with DHI, there was a trend toward lower DHI scores in males. In the subscale analysis, we found a marginal correlation between females and emotional DHI subscores and between age and functional DHI subscores (p < 0.05).

conclusionsOur study revealed a correlation between gaze position error (GPE) during rapid head movements and subacute symptoms after AUVP, explaining nearly 50% of the variance in Dizziness Handicap Inventory (DHI) scores. Additionally, emotional symptoms exhibited a gender bias, predominantly affecting females, whereas functional symptoms showed a slight dependence on age.

Indexed as

DizzinessFixation, OcularHead Impulse TestVestibular NeuronitisAdultAgedFemaleHead MovementsHumansMaleMiddle AgedReflex, Vestibulo-OcularSeverity of Illness IndexSurveys and QuestionnairesAcute unilateral vestibulopathyDizzinessDizziness Handicap InventoryGaze position errorQuality of life

Identifiers

PMID40940015
PMCPMC12904238

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.