Evidence map›Paper›PMID 40939999›Full record

Observational studyUrology2026

Postoperative Symptom Severity and Time Course After Bilateral Ureteroscopy With Stents: Results From the Study to Enhance Understanding of Stent-associated Symptoms.

Alana C Desai, Jonathan D Harper, Naim M Maalouf, Hing Hung Henry Lai, Charles D Scales, Hongqiu Yang, Gregory E Tasian, Rebecca D McCune, Hussein R Al-Khalidi, Ziya Kirkali and 2 more

Abstract readMulticenter StudyObservational StudyComparative Study
In one paragraph

Observational study in Urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alana C DesaiDepartment of Urology, University of Washington School of Medicine, Seattle, WA; Division of Urology, Department of Surgery, Washington University in St. Louis, St. Louis, MO. Electronic address: adesai10@uw.edu.
Jonathan D HarperDepartment of Urology, University of Washington School of Medicine, Seattle, WA.
Naim M MaaloufDepartment of Internal Medicine and Charles and Jane Pak Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, Dallas, TX.
Hing Hung Henry LaiDivision of Urology, Department of Surgery, Washington University in St. Louis, St. Louis, MO.
Charles D ScalesDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC; Department of Urology, Duke University School of Medicine, Durham, NC; Department of Population Health Sciences, Duke University School of Medicine, Durham, NC.
Hongqiu YangDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Gregory E TasianDivision of Urology, Children's Hospital of Philadelphia and Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Rebecca D McCuneDivision of Urology, Children's Hospital of Philadelphia and Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Hussein R Al-KhalidiDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC; Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC.
Ziya KirkaliNational Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD.
Hunter WessellsDepartment of Urology, University of Washington School of Medicine, Seattle, WA.
Jodi A AntonelliDepartment of Urology, Duke University School of Medicine, Durham, NC.

Funding

Urinary Stone Disease Research Network: Scientific Data Research CenterU01DK110988 · NIDDK · DUKE UNIVERSITY · PI AL-KHALIDI, HUSSEIN, SCALES, CHARLES D · 2016 to 2020
$6.9M
Optimizing Fluid Therapy and Stent Management in Children and Adults with NephrolithiasisU01DK110994 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI MAALOUF, NAIM M · 2016 to 2024
$5.3M
Harnessing Behavior to Decrease Urinary Stone Disease Morbidity Research ProjectU01DK110961 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI REESE, PETER PHILIP, TASIAN, GREGORY EDWARD · 2016 to 2024
$5.3M
Extension of Urinary Stone Disease Research Network (USDRN) at Washington UniversityU01DK110986 · NIDDK · WASHINGTON UNIVERSITY · PI LAI, HING HUNG HENRY · 2016 to 2024
$5.2M
UW USDRN Clinical CenterU01DK110954 · NIDDK · UNIVERSITY OF WASHINGTON · PI HARPER, JONATHAN D., WESSELLS, HUNTER · 2016 to 2024
$4.9M
Urinary Stone Disease Research Network: Scientific Data Research CenterU24DK110988 · NIDDK · DUKE UNIVERSITY · PI AL-KHALIDI, HUSSEIN, SCALES, CHARLES D · 2022 to 2024
$4.1M
NIDDK NIH HHS U01 DK110954NIDDK NIH HHS U01 DK110961NIDDK NIH HHS U01 DK110986NIDDK NIH HHS U01 DK110988NIDDK NIH HHS U01 DK110994NIDDK NIH HHS U24 DK110988
6 · The paper itself

Abstract

objectiveTo assess and compare stent-associated symptoms after unilateral vs bilateral ureteroscopy with ureteral stent placement for stone treatment.

methodsParticipants enrolled in the Study to Enhance Understanding of Stent-Associated Symptoms (STENTS), a multicenter, prospective, observational cohort study, completed validated questionnaires and patient-reported outcome measures to assess stent-associated symptoms postoperatively. Patient-Reported Outcomes Measurement Information System (PROMIS) tools were used to measure pain intensity and interference due to pain, while the Ureteral Stent Symptom Questionnaire (USSQ) and Lower Urinary Tract Dysfunction Research Network Symptom Index-10 (LURN SI-10) were used to measure urinary symptoms. These data were used to determine symptom intensity and course, comparing outcomes after bilateral vs unilateral ureteroscopy.

resultsOf the 484 participants who enrolled in STENTS, 60 underwent a bilateral procedure. Patients in the bilateral group reported greater increases in pain intensity and pain interference beginning on POD 3 (P = .017 and .022, respectively), continuing through POD 7-9, with no difference in interference 30 days after stent removal, compared to the unilateral group. Urinary symptoms were worse following a bilateral compared to unilateral procedure at all time points, except for similar urinary symptoms 30 days following stent removal.

conclusionPatients undergoing bilateral compared to unilateral ureteroscopy report higher pain intensity, pain interference and urinary symptoms. Although exploratory, this analysis provides the most informative description of the patient experience with bilateral stents to date and may be useful in counseling patients considering bilateral stone treatment and in managing expectations.

Indexed as

Postoperative ComplicationsStentsUreteral CalculiUreteroscopyAdultAgedFemaleHumansMaleMiddle AgedPatient Reported Outcome MeasuresProspective StudiesSeverity of Illness IndexTime Factors

Identifiers

PMID40939999
PMCPMC12506927

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.