Evidence map›Paper›PMID 40939329›Full record

ArticlePoultry science2025

Epidemiological investigation and genomic characterization of Gyrovirus galga1 in Guangxi, China.

Dan Yu, Yanfang Zhang, Zhixun Xie, Sisi Luo, Liji Xie, Meng Li, Tingting Zeng, Qing Fan, Minxiu Zhang, Xiaofeng Li and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Poultry science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Molecular Characterization of EmergingInternational journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Dan YuGuangXi Key Laboratory of Veterinary Biotechnology, GuangXi Veterinary Research Institute, Key Laboratory of China (GuangXi)-ASEAN Cross-Border Animal Disease Prevention and Control, Ministry of Agriculture and Rural Affairs of China, Nanning 530001, China.
Yanfang ZhangGuangXi Key Laboratory of Veterinary Biotechnology, GuangXi Veterinary Research Institute, Key Laboratory of China (GuangXi)-ASEAN Cross-Border Animal Disease Prevention and Control, Ministry of Agriculture and Rural Affairs of China, Nanning 530001, China.
Zhixun XieGuangXi Key Laboratory of Veterinary Biotechnology, GuangXi Veterinary Research Institute, Key Laboratory of China (GuangXi)-ASEAN Cross-Border Animal Disease Prevention and Control, Ministry of Agriculture and Rural Affairs of China, Nanning 530001, China. Electronic address: xiezhixun@126.com.
Sisi LuoGuangXi Key Laboratory of Veterinary Biotechnology, GuangXi Veterinary Research Institute, Key Laboratory of China (GuangXi)-ASEAN Cross-Border Animal Disease Prevention and Control, Ministry of Agriculture and Rural Affairs of China, Nanning 530001, China.
Liji XieGuangXi Key Laboratory of Veterinary Biotechnology, GuangXi Veterinary Research Institute, Key Laboratory of China (GuangXi)-ASEAN Cross-Border Animal Disease Prevention and Control, Ministry of Agriculture and Rural Affairs of China, Nanning 530001, China.
Meng LiGuangXi Key Laboratory of Veterinary Biotechnology, GuangXi Veterinary Research Institute, Key Laboratory of China (GuangXi)-ASEAN Cross-Border Animal Disease Prevention and Control, Ministry of Agriculture and Rural Affairs of China, Nanning 530001, China.
Tingting ZengGuangXi Key Laboratory of Veterinary Biotechnology, GuangXi Veterinary Research Institute, Key Laboratory of China (GuangXi)-ASEAN Cross-Border Animal Disease Prevention and Control, Ministry of Agriculture and Rural Affairs of China, Nanning 530001, China.
Qing FanGuangXi Key Laboratory of Veterinary Biotechnology, GuangXi Veterinary Research Institute, Key Laboratory of China (GuangXi)-ASEAN Cross-Border Animal Disease Prevention and Control, Ministry of Agriculture and Rural Affairs of China, Nanning 530001, China.
Minxiu ZhangGuangXi Key Laboratory of Veterinary Biotechnology, GuangXi Veterinary Research Institute, Key Laboratory of China (GuangXi)-ASEAN Cross-Border Animal Disease Prevention and Control, Ministry of Agriculture and Rural Affairs of China, Nanning 530001, China.
Xiaofeng LiGuangXi Key Laboratory of Veterinary Biotechnology, GuangXi Veterinary Research Institute, Key Laboratory of China (GuangXi)-ASEAN Cross-Border Animal Disease Prevention and Control, Ministry of Agriculture and Rural Affairs of China, Nanning 530001, China.
You WeiGuangXi Key Laboratory of Veterinary Biotechnology, GuangXi Veterinary Research Institute, Key Laboratory of China (GuangXi)-ASEAN Cross-Border Animal Disease Prevention and Control, Ministry of Agriculture and Rural Affairs of China, Nanning 530001, China.
Aiqiong WuGuangXi Key Laboratory of Veterinary Biotechnology, GuangXi Veterinary Research Institute, Key Laboratory of China (GuangXi)-ASEAN Cross-Border Animal Disease Prevention and Control, Ministry of Agriculture and Rural Affairs of China, Nanning 530001, China.
Lijun WanGuangXi Key Laboratory of Veterinary Biotechnology, GuangXi Veterinary Research Institute, Key Laboratory of China (GuangXi)-ASEAN Cross-Border Animal Disease Prevention and Control, Ministry of Agriculture and Rural Affairs of China, Nanning 530001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gyrovirus galga1 (GyG1), an emerging pathogen within the Anelloviridae family, exhibits expanding host diversity and zoonotic potential, yet its epidemiological patterns and genomic determinants remain poorly characterized. To address this critical knowledge gap, we conducted the first comprehensive molecular epidemiological investigation of GyG1 in Guangxi, China (2020-2025). The result revealed three key advances: (1) Molecular-epidemiological evidence of winter-spring seasonality and age-dependent transmission, with breeder chickens showing biphasic peaks (1-6 and > 21 weeks) contrasting broilers' progressive carriage; (2) Genomic characterization revealing VP1-VP3 as nuclear-localized hydrophilic proteins, identifying VP1 nuclear targeting as a therapeutic vulnerability; (3) Functional annotation of recombination-driven evolution, including a temporal paradox in strain KX708518's ancestry. This study elucidates GyG1's ecological dynamics in a high-density poultry region and provides critical data for One Health surveillance and vaccine development, addressing a key gap in gyrovirus countermeasures.

Indexed as

ChickensCircoviridae InfectionsGenome, ViralGyrovirusPoultry DiseasesAnimalsChinaPhylogenySeasonsComplete genomeGene functionGyrovirus galga1Phylogenetic analysisPrevalence

Identifiers

PMID40939329
PMCPMC12683125

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.