ArticleLangmuir : the ACS journal of surfaces and colloids2025
Wireless Power-Up and Readout of Label-Free Nanosensors for In-Vivo Monitoring of Protein Concentrations in Live Animals.
Article in Langmuir : the ACS journal of surfaces and colloids, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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5 authors.
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Abstract
Tracking inflammatory biomarkers in real-time is essential for timely clinical interventions; however, wired sensors are restrictive, inconvenient, prone to infection risk, and limit continuous monitoring compared with wireless sensors. In this study, for the first time ever, to the best of our knowledge, we report a novel method for wireless power-up and readout of a label-free electronic biosensor for quantification of protein biomarkers in live animals. The sensor operates through resonant inductive coupling for wireless power transfer, enabling remote impedance measurements of a nanowell array without requiring a direct electrical connection. The receiver circuit is integrated within a 3D-printed structure optimized for application on wound sites. Experimental validation included titration of IL-6 across a wide concentration range and in vivo testing on 30 animals with induced wounds. The wireless sensor's measurements showed a strong correlation (
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