ArticlePloS one2025
Characteristics of quantitative dynamic contrast-enhanced magnetic resonance imaging for orbital space-occupying lesions: A retrospective case series study.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to compare the differences in the quantitative parameters of quantitative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) across various types of orbital space-occupying lesions and to explore the diagnostic efficacy of DCE-MRI in the diagnosis of malignant orbital tumors.Meanwhile,to compare the differences in the quantitative parameters of DCE-MRI across vascular malformations, benign tumors, and malignant orbital lesions,and to explore the diagnostic efficacy of DCE-MRI introducing a novel grouping strategy that distinguishes vascular malformations from solid tumors.
methodsIn this retrospective case series study, patients were classified into three groups: vascular malformations, benign lesions, and malignant lesions. We analyzed the differences in the quantitative parameters and time-intensity curve (TIC) profiles among the three groups. The diagnostic efficacy of the quantitative parameters in the diagnosis of orbital malignant lesions was analyzed using receiver operating characteristic (ROC) curves.
resultsThe differences in TIC compositions among the three groups were statistically significant (P < 0.05).The differences in volume transfer constant(Ktrans) value,rate constant(Kep) value,and area under curve(iAUC) among the three groups exhibited statistically significant differences (P < 0.05). All three diagnostic parameters(Ktrans, Kep, and iAUC) demonstrated effectiveness in diagnosing malignant lesions. The area under the ROC curve values for Ktrans, Kep, and iAUC were 0.759, 0.764, and 0.752, respectively, indicating adequate diagnostic value.
conclusionsThe composition ratios of the TIC for vascular malformations, benign lesions, and malignant lesions differed considerably. Ktrans, Kep, and iAUC can serve as valuable references for the differential diagnosis of orbital space-occupying lesions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.