ArticleAnalytical chemistry2025
Coupling Drift Tube Ion Mobility Measurements with Charge Detection Mass Spectrometry for the Analysis of Virus-like Particles and Other Megadalton-Sized Ions.
Article in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Accurate Sizing and Resolution of Nominal 200 nm Diameter Polystyrene Nanospheres With Charge Detection Mass Spectrometry.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
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Authors and funding
5 authors.
Funding
Abstract
The coupling of ion mobility (IM) measurements and mass spectrometry (IM-MS) has provided valuable structural information for gas phase ions and helped to resolve complex mixtures. However, the mass range of conventional MS is limited by the loss of charge state resolution, and this has essentially precluded the application of IM-MS methods to large particles and complexes with masses in the megadalton regime (and beyond) as well as to heterogeneous and complex mixtures in general. Single particle measurements can overcome the limitations of conventional MS and enable mass measurements for heterogeneous and high mass samples. In the work presented below, we describe the coupling of IM measurements with charge detection mass spectrometry (CD-MS). In CD-MS, ions oscillate back and forth through a detection cylinder embedded in an electrostatic linear ion trap. Charge and
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