Evidence map›Paper›PMID 40938692›Full record

ArticleHuman vaccines & immunotherapeutics2025

Successes, lessons learned and recommendations for the future: Experiences from the first year of Ontario's nirsevimab program for respiratory syncytial virus (RSV) prophylaxis in infants.

Bosco Paes, Erin Fleischer, Jane Healey, Eddy Lau, Graeme N Smith

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bosco PaesDepartment of Pediatrics, McMaster University, & Neonatal Division, McMaster Children's Hospital, Hamilton Health Sciences, Hamilton, Ontario, Canada.ORCID 0000-0002-3308-2706
Erin FleischerChildren's Hospital, London Health Sciences Centre, London, Ontario, Canada.
Jane HealeyWomen's and Children's Program, Trillium Health Partners, Mississauga, Ontario, Canada.
Eddy LauDepartment of Paediatrics, University of Toronto, Unity Health Toronto - St. Joseph's Health Centre, Toronto, Ontario, Canada.
Graeme N SmithDepartment of Obstetrics & Gynecology, Queen's University, Kingston Health Sciences Centre, Kingston, Ontario, Canada.ORCID 0000-0002-3128-4523

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At the conclusion of the 2024/2025 respiratory syncytial virus (RSV) season in Ontario, a panel of healthcare providers who were actively involved in the conduct of the province's first RSV prophylaxis program with nirsevimab in infants, assembled to discuss their experiences. The discussion was a follow-up to a larger pre-RSV season meeting held in June 2024 to develop recommendations supporting a universal prophylaxis program for infants in Ontario. The principal objective of the 2025 meeting was to identify components of the province's program that were successful, as well as those that posed barriers to nirsevimab uptake. A modified version of the World Health Organization's analytical framework for health systems was used to structure the discussion around five key programmatic building blocks: (1) governance and leadership, (2) funding and reimbursement, (3) logistics, demand and distribution, (4) awareness and education, and (5) surveillance and monitoring. A consensus was reached on updated recommendations to enhance the success of Ontario's nirsevimab program for future RSV seasons. These recommendations aim to ensure equitable access for all infants, achieve optimal uptake, and provide the best protection against RSV infection for Ontario's infants.

Indexed as

Antibodies, Monoclonal, HumanizedAntiviral AgentsRespiratory Syncytial Virus InfectionsHumansInfantOntarioRespiratory Syncytial Virus, HumanAntibodies, Monoclonal, HumanizedAntiviral AgentsCanadainfantsnirsevimabpassive immunizationprogram deliverypublic healthRespiratory syncytial virus (RSV)

Identifiers

PMID40938692
PMCPMC12456209

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.