Evidence map›Paper›PMID 40938672›Full record

ArticleJournal of the American Society of Nephrology : JASN2026

Mycophenolate Mofetil versus Cyclophosphamide for Initial Therapy in Childhood-Onset Proliferative Lupus Nephritis: A Prospective, Multicenter, Randomized Trial.

Ying Wang, Xiaoyan Li, Shan Jian, Jing Li, Junxia Yan, Shuzhen Sun, Zhenle Yang, Weimin Zheng, Qun Li, Qi Zheng and 32 more

Registry-linked trialAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07719140 (Low- Versus High-Dose Initial Glucocorticoid Therapy for Childhood-Onset Proliferative Lupus Nephritis), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07719140 phase4recruitingnot on this map

Low- Versus High-Dose Initial Glucocorticoid Therapy for Childhood-Onset Proliferative Lupus Nephritis: a Multicenter Open-Label Noninferiority Randomized Controlled Trial

TypeinterventionalSponsorPeking Union Medical College HospitalRan2026 to 2029Enrolled198ConditionsChildhood-onset Systemic Lupus Erythematosus, Lupus Nephritis (LN)ArmsHigh-dose prednisone, Low-dose prednisone
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Is It Time to Change Our Approach to Childhood Lupus Nephritis?Journal of the American Society of Nephrology : JASN · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors.

Ying WangDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, China.ORCID 0000-0002-4506-3641
Xiaoyan LiDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, China.ORCID 0000-0001-5031-8875
Shan JianDepartment of Pediatrics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.ORCID 0000-0001-6587-8146
Jing LiDepartment of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.ORCID 0000-0003-2504-1629
Junxia YanDepartment of Epidemiology and Health Statistics and Hunan Provincial Key Laboratory of Clinical Epidemiology, Xiangya School of Public Health, Central South University, Changsha, China.ORCID 0000-0001-6067-1613
Shuzhen SunDepartment of Pediatric Nephrology and Rheumatology and Immunology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Zhenle YangDepartment of Pediatric Nephrology and Rheumatology and Immunology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Weimin ZhengDepartment of Nephrology, Jiangxi Provincial Children's Hospital, Nanchang, China.ORCID 0009-0004-0454-0028
Qun LiDepartment of Nephrology, Jiangxi Provincial Children's Hospital, Nanchang, China.ORCID 0009-0007-7792-370
Qi ZhengDepartment of Rheumatology Immunology and Allergy, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0002-3182-4235
Meiping LuDepartment of Rheumatology Immunology and Allergy, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Mo WangDepartment of Nephrology, Children's Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0003-1673-3631
Qin YangDepartment of Nephrology, Children's Hospital of Chongqing Medical University, Chongqing, China.
Huawei MaoDepartment of Rheumatology and lmmunology, Beijing Children's Hospital, National Center for Children's Health, Capital Medical University, Beijing, China.ORCID 0000-0001-8807-9267
Tongxin HanDepartment of Rheumatology and lmmunology, Beijing Children's Hospital, National Center for Children's Health, Capital Medical University, Beijing, China.
Yi LinDepartment of Pediatric Nephrology and Rheumatology, Affiliated Hospital of Qingdao University, Qingdao, China.
Qiuye ZhangDepartment of Pediatric Nephrology and Rheumatology, Affiliated Hospital of Qingdao University, Qingdao, China.
Yue DuDepartment of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, China.
Ying TangDepartment of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, China.ORCID 0000-0001-9685-3152
Yong CaiDepartment of Pediatrics, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID 0009-0009-7769-2723
Liangzhong SunDepartment of Pediatrics, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID 0000-0003-1962-8626
Jianjiang ZhangDepartment of Pediatrics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0000-0003-2953-1924
Junmei LiuDepartment of Pediatrics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zanhua RongDepartment of Pediatrics, the Second Hospital of Hebei Medical University, Shijiazhuang, China.ORCID 0000-0001-8056-5009
Lijun JiangDepartment of Pediatrics, the Second Hospital of Hebei Medical University, Shijiazhuang, China.ORCID 0000-0002-5747-1116
Haitao BaiThe First Affiliated Hospital of Xiamen University, Xiamen, China.
Yan ChenThe First Affiliated Hospital of Xiamen University, Xiamen, China.
Jun YangDepartment of Rheumatology and Immunology, Shenzhen Children's Hospital, Shenzhen, China.
Linlin WangDepartment of Rheumatology and Immunology, Shenzhen Children's Hospital, Shenzhen, China.ORCID 0000-0001-9501-5544
Wei ZhangPediatric Immunology and Rheumatology Department, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.ORCID 0009-0006-3750-9312
Xinyi WeiPediatric Immunology and Rheumatology Department, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.ORCID 0009-0004-3152-3901
Yun ZhuDepartment of Nephrology and Immunology, Children's Hospital of Soochow University, Suzhou, China.
Xiaozhong LiDepartment of Nephrology and Immunology, Children's Hospital of Soochow University, Suzhou, China.
Xingyuan XieDepartment of Pediatric Nephrology, Rheumatology and Immunology, the First People's Hospital of Chenzhou, Chenzhou, China.
Dujuan ZhouDepartment of Pediatric Nephrology, Rheumatology and Immunology, the First People's Hospital of Chenzhou, Chenzhou, China.ORCID 0009-0004-4565-1496
Yongzhen LiDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, China.
Yan CaoDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, China.
Tian ShenDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, China.
Qian LiuDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, China.
Hongmei SongDepartment of Pediatrics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.ORCID 0000-0001-9801-2517
Xiaochuan WuDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, China.ORCID 0000-0003-4562-141
Chinese Alliance of Pediatric Rheumatic and Immunologic Diseases

Funding

National Key Research and Development Program of China (CN) 2021YFC2702004
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

chronic GNchronic kidney diseasechronic nephropathyclinical nephrologyclinical trialimmunosuppressionlupus nephritispediatric nephrologypediatricsSLE

Identifiers

PMID40938672
PMCPMC12935383

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.