Evidence map›Paper›PMID 40938657›Full record

ArticleJournal of Parkinson's disease2025

Differences in intestinal microbiota in Parkinson's disease and isolated REM sleep behavior disorder.

Alba Troci, Julienne Haas, Anna Weiß, Sebastian Heinzel, Andre Franke, Daniela Berg, Corinna Bang, Eva Schaeffer

Abstract read
In one paragraph

Article in Journal of Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alba TrociInstitute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany.ORCID 0000-0003-1000-7217
Julienne HaasDepartment of Neurology, Christian-Albrechts-University, Kiel, Germany.ORCID 0009-0004-3539-9362
Anna WeißDepartment of Neurology, Christian-Albrechts-University, Kiel, Germany.ORCID 0009-0001-2112-4796
Sebastian HeinzelDepartment of Neurology, Christian-Albrechts-University, Kiel, Germany.ORCID 0000-0003-4516-0529
Andre FrankeInstitute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany.ORCID 0000-0003-1530-5811
Daniela BergDepartment of Neurology, Christian-Albrechts-University, Kiel, Germany.ORCID 0000-0001-5796-5442
Corinna BangInstitute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany.ORCID 0000-0001-6814-6151
Eva SchaefferDepartment of Neurology, Christian-Albrechts-University, Kiel, Germany.ORCID 0000-0002-0792-4383

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have shown differences in the microbiota of patients with Parkinson's disease (PD) compared to healthy controls (HC). To deduce a possible causality, it is highly relevant to examine changes in the prodromal phase. This study investigated the microbiome in stool samples of individuals with isolated REM sleep behavior disorder (iRBD, n = 32) compared to clinical PD (n = 23) and HC (n = 34) and showed significant changes of beta-diversity in PD and iRBD patients compared to HC (

Indexed as

Gastrointestinal MicrobiomeParkinson DiseaseREM Sleep Behavior DisorderAgedFecesFemaleHumansMaleMiddle Aged16S rDNA sequencingGut microbiotaParkinson's diseaseREM sleep behavior disorder

Identifiers

PMID40938657
PMCPMC13347513

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.