Evidence map›Paper›PMID 40938651›Full record

ArticleJournal of bacteriology2025

Characterization of two co-regulated response regulators in

Caitlin Lee Williams, Anchal Mehra, Emily K Harrison, Cynthia G Thomas, Jack Riley Palmer, D Kane Cooper, Elizabeth M Garrett, Rita Tamayo

Abstract read
In one paragraph

Article in Journal of bacteriology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Phase variable colony morphotypes ofInfection and immunity · 2026
    Article
  2. Phase variable colony morphotypes ofbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Caitlin Lee WilliamsDepartment of Biology, Virginia Wesleyan University, Virginia Beach, Virginia, USA.ORCID 0000-0002-6498-7700
Anchal MehraDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0003-2738-713X
Emily K HarrisonDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Cynthia G ThomasDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Jack Riley PalmerDepartment of Biology, Virginia Wesleyan University, Virginia Beach, Virginia, USA.
D Kane CooperDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0002-7781-4550
Elizabeth M GarrettDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Rita TamayoDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0002-3745-3316

Funding

SEEDING POSTDOCTORAL INNOVATORS IN RESEARCH &EDUCATIONK12GM000678 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DONALD T LYSLE, Kathryn Joanna Reissner · 1999 to 2026
$30.9M
UNC PREP in the Biomedical Sciences - Administrative SupplementR25GM089569 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROBINSON, DONITA L, RODRIGUEZ-ROMAGUERA, JOSE · 2010 to 2024
$5.6M
Global regulation in Clostridium difficile via phase variation of cyclic diguanylate signalingR01AI143638 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI TAMAYO, RITA · 2019 to 2023
$2.5M
NIAID NIH HHS R01 AI143638NIGMS NIH HHS K12 GM000678NIGMS NIH HHS R25 GM089569NIH HHS K12-GM000678NIH HHS R01-AI143638NIH HHS R25-GM089569
6 · The paper itself

Abstract

As an obligate anaerobe,

Indexed as

Bacterial ProteinsClostridioides difficileGene Expression Regulation, BacterialEscherichia coliProtein MultimerizationSignal TransductionBacterial ProteinsC. difficilepathogenesisreceiver domainresponse regulatortwo-component system

Identifiers

PMID40938651
PMCPMC12548384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.