Evidence map›Paper›PMID 40938561›Full record

ArticleJapanese journal of radiology2026

Assessing accuracy and legitimacy of multimodal large language models on Japan Diagnostic Radiology Board Examination.

Yuichiro Hirano, Soichiro Miki, Yosuke Yamagishi, Shouhei Hanaoka, Takahiro Nakao, Tomohiro Kikuchi, Yuta Nakamura, Yukihiro Nomura, Takeharu Yoshikawa, Osamu Abe

Abstract readComparative Study
In one paragraph

Article in Japanese journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Large-scale evaluation of multimodal large language models for pneumothorax detection.Diagnostic and interventional radiology (Ankara, Turkey) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuichiro HiranoDepartment of Radiology, the University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, Japan. yhirano-tky@umin.ac.jp.ORCID http://orcid.org/0000-0003-1564-0513
Soichiro MikiDepartment of Computational Diagnostic Radiology and Preventive Medicine, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, Japan.ORCID http://orcid.org/0000-0001-6365-6531
Yosuke YamagishiDepartment of Radiology, the University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, Japan.ORCID http://orcid.org/0009-0006-7688-3075
Shouhei HanaokaDepartment of Computational Diagnostic Radiology and Preventive Medicine, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, Japan.ORCID http://orcid.org/0000-0002-7496-1651
Takahiro NakaoDepartment of Computational Diagnostic Radiology and Preventive Medicine, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, Japan.ORCID http://orcid.org/0000-0001-9498-7501
Tomohiro KikuchiDepartment of Computational Diagnostic Radiology and Preventive Medicine, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, Japan.ORCID http://orcid.org/0000-0002-4222-4569
Yuta NakamuraDepartment of Computational Diagnostic Radiology and Preventive Medicine, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, Japan.ORCID http://orcid.org/0000-0001-6962-6704
Yukihiro NomuraDepartment of Computational Diagnostic Radiology and Preventive Medicine, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, Japan.ORCID http://orcid.org/0000-0001-6471-9936
Takeharu YoshikawaDepartment of Computational Diagnostic Radiology and Preventive Medicine, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, Japan.ORCID http://orcid.org/0000-0002-1924-5468
Osamu AbeDepartment of Radiology, the University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, Japan.ORCID http://orcid.org/0000-0002-1180-2629

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess and compare the accuracy and legitimacy of multimodal large language models (LLMs) on the Japan Diagnostic Radiology Board Examination (JDRBE). MATERIALS AND

methodsThe dataset comprised questions from JDRBE 2021, 2023, and 2024, with ground-truth answers established through consensus among multiple board-certified diagnostic radiologists. Questions without associated images and those lacking unanimous agreement on answers were excluded. Eight LLMs were evaluated: GPT-4 Turbo, GPT-4o, GPT-4.5, GPT-4.1, o3, o4-mini, Claude 3.7 Sonnet, and Gemini 2.5 Pro. Each model was evaluated under two conditions: with inputting images (vision) and without (text-only). Performance differences between the conditions were assessed using McNemar's exact test. Two diagnostic radiologists (with 2 and 18 years of experience) independently rated the legitimacy of responses from four models (GPT-4 Turbo, Claude 3.7 Sonnet, o3, and Gemini 2.5 Pro) using a five-point Likert scale, blinded to model identity. Legitimacy scores were analyzed using Friedman's test, followed by pairwise Wilcoxon signed-rank tests with Holm correction.

resultsThe dataset included 233 questions. Under the vision condition, o3 achieved the highest accuracy at 72%, followed by o4-mini (70%) and Gemini 2.5 Pro (70%). Under the text-only condition, o3 topped the list with an accuracy of 67%. Addition of image input significantly improved the accuracy of two models (Gemini 2.5 Pro and GPT-4.5), but not the others. Both o3 and Gemini 2.5 Pro received significantly higher legitimacy scores than GPT-4 Turbo and Claude 3.7 Sonnet from both raters.

conclusionRecent multimodal LLMs, particularly o3 and Gemini 2.5 Pro, have demonstrated remarkable progress on JDRBE questions, reflecting their rapid evolution in diagnostic radiology. Eight multimodal large language models were evaluated on the Japan Diagnostic Radiology Board Examination. OpenAI's o3 and Google DeepMind's Gemini 2.5 Pro achieved high accuracy rates (72% and 70%) and received good legitimacy scores from human raters, demonstrating steady progress.

Indexed as

CertificationEducational MeasurementLarge Language ModelsMultimodal ImagingRadiologyClinical CompetenceDatasets as TopicHumansJapanSpecialty BoardsArtificial Intelligence (AI)ChatGPTLarge Language Model (LLM)MultimodalReasoning ModelVision-language Model (VLM)

Identifiers

PMID40938561
PMCPMC12769535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.