ArticleJournal of fluorescence2025
Luminescence Insights to Binding and Conformational Analysis of Graphene Oxide - Pepsin system: A Multi-Spectroscopic and In-Silico Approach.
Article in Journal of fluorescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- A Selective Pyridinedicarbohydrazide-based "naked-eye" Fluorescent Probe for Detecting CuJournal of fluorescence · 2025Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pepsin is a key proteolytic enzyme involved in the gastric digestion. Graphene oxide (GO) despite the promising biomedical applications, lacks consensus for its use in medicines. One of the leading causes in this respect is the limited understanding of its interaction with model proteins. In this background, the present study investigates the biophysical interaction of GO with pepsin using UV-Vis, Fluorescence, FT-IR spectroscopy, and in-silico modelling. UV-Vis spectra of pepsin revealed slight hypsochromic and hyperchromic shift in the presence of GO indicating alteration in pepsin's structure corroborated by fluorescence quenching study. Further analysis of fluorescence data shows a decrease in Stern-Volmer quenching constant, K
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