Evidence map›Paper›PMID 40938471›Full record

ArticleThe European physical journal. E, Soft matter2025

Subdiffusion from competition between multi-exponential friction memory and energy barriers.

Anton Klimek, Benjamin A Dalton, Roland R Netz

Abstract read
In one paragraph

Article in The European physical journal. E, Soft matter, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Hierarchical friction memory leads to subdiffusive configurational dynamics of fast-folding proteins.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anton KlimekFachbereich Physik, Freie Universität Berlin, Arnimalle 14, 14195, Berlin, Germany.ORCID http://orcid.org/0009-0008-5853-3092
Benjamin A DaltonFachbereich Physik, Freie Universität Berlin, Arnimalle 14, 14195, Berlin, Germany.
Roland R NetzFachbereich Physik, Freie Universität Berlin, Arnimalle 14, 14195, Berlin, Germany. rnetz@physik.fu-berlin.de.

Funding

Deutsche Forschungsgemeinschaft CRC 1449 "Dynamic Hydrogels at Biointerfaces"Deutsche Forschungsgemeinschaft Project A03Deutsche Forschungsgemeinschaft Project ID 431232613
6 · The paper itself

Abstract

Subdiffusion is a hallmark of complex systems, ranging from protein folding to transport in viscoelastic media. However, despite its pervasiveness, the mechanistic origins of subdiffusion remain contested. Here, we analyze both Markovian and non-Markovian dynamics, in the presence and absence of energy barriers, in order to disentangle the distinct contributions of memory-dependent friction and energy barriers to the emergence of subdiffusive behavior. Focusing on the mean squared displacement (MSD), we develop an analytical framework that connects subdiffusion to multi-scale memory effects in the generalized Langevin equation (GLE), and derive the subdiffusive scaling behavior of the MSD for systems governed by multi-exponential memory kernels. We identify persistence and relaxation timescales that delineate dynamical regimes in which subdiffusion arises from either memory or energy barrier effects. By comparing analytical predictions with simulations, we confirm that memory dominates the overdamped dynamics for barrier heights up to approximately

Identifiers

PMID40938471
PMCPMC12431924

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.