Evidence map›Paper›PMID 40938405›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

MRI-based endplate bone quality scoring system in cervical OPLL: a novel measuring method predicting titanium mesh cage subsidence following ACCF.

Minming Lu, Cen Liang, Yifan Tang, Changjiang Gu, Bin Shi, Yi Li, Bo Yuan, Xinyuan Liao, Xiongsheng Chen

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Minming LuPain Medicine Department, Chengdu Wenjiang District People's Hospital, Chengdu, China.
Cen LiangThe 3rd Affiliated Hospital of Chengdu Medical College & Pidu District People's Hospital, Chengdu, China.
Yifan TangDepartment of Orthopaedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Changjiang GuDepartment of Orthopaedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Bin ShiPain Medicine Department, Chengdu Wenjiang District People's Hospital, Chengdu, China.
Yi LiPain Medicine Department, Chengdu Wenjiang District People's Hospital, Chengdu, China.
Bo YuanSpine Center, Department of Orthopaedics, Changzheng Hospital Naval Medical University (Second Military Medical University), Shanghai, China.
Xinyuan LiaoSpine Center, Department of Orthopaedics, Changzheng Hospital Naval Medical University (Second Military Medical University), Shanghai, China. peterison@163.com.
Xiongsheng ChenDepartment of Orthopaedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. chenxiongsheng@vip.sohu.com.

Funding

National Natural Science Foundation of China 8237090980
6 · The paper itself

Abstract

purposeWhat are the optimal image magnification ratios for EBQ score measurement and the accuracy of this score in predicting titanium mesh cage (TMC) subsidence in patients with cervical ossification of the posterior longitudinal ligament (OPLL) after anterior cervical corpectomy and fusion (ACCF)?

methods107 cervical OPLL patients who had undergone single-level ACCF were included. Patients were stratified into subsidence and non-subsidence groups, paired by propensity score matching, and the predictive values of EBQ and VBQ scores for TMC subsidence were evaluated via receiver operating curve (ROC) and the area under the curve (AUC).

resultsOn radiographs, 75% and 100% magnifications showed better reliability than 25% and 50%, thus 75% was used. Higher EBQ, Global VBQ, U-L VBQ scores and older age are linked to higher TMC subsidence risk. In the cohort of matched patients, An EBQ threshold of 2.44 demonstrated predictive efficacy for TMC subsidence (AUC = 0.752, 78.8% sensitivity, 69.7% specificity). A U-L VBQ score threshold of 2.57 and Global VBQ score threshold of 2.56 both demonstrated good prediction of TMC subsidence. The former achieved 84.8% sensitivity and 57.6% specificity, while the latter showed 86.3% sensitivity with 52.4% specificity. The two matched groups had similar improvements in patient-reported outcomes including VAS score, NDI and mJOA score.

conclusionHigher EBQ score was an independent factor for TMC subsidence. Use of EBQ score of 2.44 as the cutoff value on preoperative MRIs magnified 75% yielded better reliability. Regarding the two scores, the EBQ score emerges as a more effective predictor.

Indexed as

Cervical VertebraeMagnetic Resonance ImagingOssification of Posterior Longitudinal LigamentSpinal FusionSurgical MeshAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTitaniumTitaniumAnterior cervical corpectomy and fusionEBQ scoreOssification of the posterior longitudinal ligamentTitanium mesh cage subsidenceVBQ score

Identifiers

PMID40938405

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.