Evidence map›Paper›PMID 40938235›Full record

ReviewThe Journal of hand surgery2025

Opioid-Free Pain Management Strategies for Patients on Oral Anticoagulation Undergoing Soft Tissue Hand Surgery.

Ellis M Berns, Thompson Zhuang, Hannah H Lee

Abstract readReview
In one paragraph

Review in The Journal of hand surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ellis M BernsDepartment of Orthopedic Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA.
Thompson ZhuangDepartment of Orthopedic Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA.
Hannah H LeeDepartment of Orthopedic Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA. Electronic address: hoeunhlee@gmail.com.

Funding

RRD VA I50 RX004845RRD VA IK2 RX003947
6 · The paper itself

Abstract

Non-narcotic multimodal analgesia has become standard for patients undergoing soft tissue hand surgery. These regimens often include nonsteroidal anti-inflammatory drugs such as ketorolac and ibuprofen, which can elevate bleeding risks in patients on anticoagulation therapy. This review aims to (1) elucidate the physiology of coagulation in relation to nonsteroidal anti-inflammatory drugs and anticoagulants, (2) examine the current surgical literature on risks and benefits of limited-duration nonsteroidal anti-inflammatory drug use in anticoagulated patients, (3) identify viable pain management alternatives, and (4) highlight areas warranting further research in nonopioid analgesia for anticoagulated patients.

Indexed as

AnticoagulantsAnti-Inflammatory Agents, Non-SteroidalHandPain ManagementPostoperative PainAdministration, OralAnalgesics, Non-NarcoticHumansAnalgesics, Non-NarcoticAnticoagulantsAnti-Inflammatory Agents, Non-SteroidalAnticoagulationbleedingNSAIDopioid

Identifiers

PMID40938235
PMCPMC12782615

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.