Evidence map›Paper›PMID 40938188›Full record

ArticleeLife2025

Gene regulatory mechanisms guiding bifurcation of inhibitory and excitatory neuron lineages in the mouse anterior brainstem.

Sami Kilpinen, Lassi Virtanen, Silvana Bodington Celma, Amos Bonsdorff, Heidi Heliölä, Kaia Achim, Juha Partanen

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sami KilpinenMolecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0003-3444-2539
Lassi VirtanenMolecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
Silvana Bodington CelmaMolecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
Amos BonsdorffMolecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
Heidi HeliöläMolecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
Kaia AchimMolecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0003-3723-4065
Juha PartanenMolecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0001-8850-4825

Funding

Magnus Ehrnroothin Säätiö 2021/2024Research Council of Finland 331261/362600Sigrid Jusélius Foundation 1119
6 · The paper itself

Abstract

Selector transcription factors (TFs) control choices of alternative cellular fates during development. The ventral rhombomere 1 of the embryonic mouse (

Indexed as

Brain StemCell LineageGABAergic NeuronsGene Expression Regulation, DevelopmentalNeuronsAnimalsCell DifferentiationGATA2 Transcription FactorGATA3 Transcription FactorMiceT-Cell Acute Lymphocytic Leukemia Protein 1Gata2 protein, mouseGATA2 Transcription FactorGata3 protein, mouseGATA3 Transcription FactorTal1 protein, mouseT-Cell Acute Lymphocytic Leukemia Protein 1brainstemcell biologydevelopmental biologydifferentiationmouseneurobiology

Identifiers

PMID40938188
PMCPMC12431775

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.