Evidence map›Paper›PMID 40938133›Full record

ArticleJournal of natural products2025

Halogenation-Guided Chemical Screening Uncovers Cyanobacterin Analogues from the Cyanobacterium

Franziska Schanbacher, Arthur Guljamow, Valerie I C Rebhahn, Peter Schmieder, Heike Enke, Elke Dittmann, Martin Baunach, Timo H J Niedermeyer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of natural products, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Franziska SchanbacherDepartment of Pharmaceutical Biology, Institute of Pharmacy, Freie Universität Berlin, 14195 Berlin, Germany.ORCID 0009-0005-8750-6454
Arthur GuljamowInstitute for Biochemistry and Biology, University of Potsdam, 14476 Potsdam, Germany.ORCID 0000-0002-8911-4332
Valerie I C RebhahnDepartment of Pharmaceutical Biology, Institute of Pharmacy, Freie Universität Berlin, 14195 Berlin, Germany.ORCID 0000-0003-1527-6299
Peter SchmiederLeibniz-Forschungsinstitut für Molekulare Pharmakologie, Department of NMR-Supported Structural Biology, 13125 Berlin, Germany.ORCID 0000-0001-9968-9327
Heike EnkeSimris Biologics GmbH, 12489 Berlin, Germany.
Elke DittmannInstitute for Biochemistry and Biology, University of Potsdam, 14476 Potsdam, Germany.ORCID 0000-0002-7549-7918
Martin BaunachInstitute of Pharmaceutical Biology, University of Bonn, 53115 Bonn, German.ORCID 0000-0003-0822-1468
Timo H J NiedermeyerDepartment of Pharmaceutical Biology, Institute of Pharmacy, Freie Universität Berlin, 14195 Berlin, Germany.ORCID 0000-0003-1779-7899

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Halogenated specialized metabolites show high chemical diversity and exhibit a range of biological activities. A targeted screening of a cyanobacteria extract library for halogenated specialized metabolites using HPLC-HRMS combined with MassQL and Haloseeker indicated that several of the extracts contained halogenated compounds, among them an extract of

Indexed as

CyanobacteriaPeptides, CyclicHalogenationHumansMolecular StructurecyanobactinsPeptides, Cyclic

Identifiers

PMID40938133
PMCPMC12481558

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.