Evidence map›Paper›PMID 40938099›Full record

ArticleJournal of virology2025

Ebola virus' hidden target: virus transmission to and infection of skin.

Paige T Richards, Anthony M Fleck, Radhika Patel, Maryam Fakhimi, Dana Bohan, Kathleen Geoghegan-Barek, Anna N Honko, Allison E Stolte, Caroline B Plescia, Caitlin O Messingham and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Mapping FirstbioRxiv : the preprint server for biology · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Paige T RichardsDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0002-9488-3101
Anthony M FleckDepartment of Dermatology, University of Iowa, Iowa City, Iowa, USA.
Radhika PatelDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
Maryam FakhimiDepartment of Dermatology, University of Iowa, Iowa City, Iowa, USA.
Dana BohanDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
Kathleen Geoghegan-BarekNEIDL, Boston University, Boston, Massachusetts, USA.
Anna N HonkoNEIDL, Boston University, Boston, Massachusetts, USA.ORCID 0000-0001-9165-148X
Allison E StolteDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
Caroline B PlesciaDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
Caitlin O MessinghamDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
Samuel J ConnellDepartment of Dermatology, University of Iowa, Iowa City, Iowa, USA.
Tyler P CroweDepartment of Dermatology, University of Iowa, Iowa City, Iowa, USA.
Francoise A GourroncDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
Ricardo CarrionTexas Biomedical Research Institute, San Antonio, Texas, USA.
Anthony GriffithsNEIDL, Boston University, Boston, Massachusetts, USA.
David K MeyerholzDepartment of Pathology, University of Iowa, Iowa City, Iowa, USA.
Aloysius J KlingelhutzDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.
Robert A DaveyNEIDL, Boston University, Boston, Massachusetts, USA.
Kelly N MessinghamDepartment of Dermatology, University of Iowa, Iowa City, Iowa, USA.
Wendy MauryDepartment of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0002-9892-4484

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Jon C.D. Houtman · 2000 to 2026
$70.0M
EXTRAMURAL RES FACIL CONST: REPRODUCTIVE, GROWTH &DVMT, MENOPAUSEC06RR020141 · NCRR · UNIVERSITY OF WISCONSIN MADISON · PI CADWALLADER, MARTIN · 2004 to 2004
$3.6M
Modeling Filovirus Infection of and Trafficking through SkinR01AI134733 · NIAID · UNIVERSITY OF IOWA · PI MAURY, WENDY JEAN · 2018 to 2021
$3.1M
Training in Molecular Virology, Viral Pathogenesis and Viral VectorsT32AI007533 · NIAID · UNIVERSITY OF IOWA · PI Stanley Perlman · 1998 to 2026
$2.5M
EXTRAMURAL REGIONAL FACILITIES CONSTRUCTIONC06RR015459 · NCRR · UNIVERSITY OF WISCONSIN MADISON · PI CADWALLADER, MARTIN · 2000 to 2000
$1.9M
Identifying placental tissue tropism and cellular mechanisms of Ebola Virus transmission from mother to fetus in pregnancyUH2AI186375 · NIAID · UNIVERSITY OF IOWA · PI MAURY, WENDY JEAN · 2024 to 2025
$625k
NCI NIH HHS P30 CA086862NCRR NIH HHS C06 RR015459NCRR NIH HHS C06 RR020141NIAID NIH HHS R01 AI134733NIAID NIH HHS T32 AI007533NIAID NIH HHS UH2 AI186375NIH HHS P51 OD011106
6 · The paper itself

Abstract

Ebola virus (EBOV), the causative agent of Ebola virus disease, remains one of the World Health Organization's top 10 threats to global health. Infectious EBOV virions can be found on the surface of skin late in infection and may be transmitted to others through skin-to-skin contact. We investigate

Indexed as

EbolavirusHemorrhagic Fever, EbolaSkinAnimalsAxl Receptor Tyrosine KinaseHumansMiceReceptor Protein-Tyrosine KinasesViral LoadViral TropismVirus InternalizationAxl Receptor Tyrosine KinaseReceptor Protein-Tyrosine Kinasesanimal modelEbola virusfilovirusskintropism

Identifiers

PMID40938099
PMCPMC12548420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.