Evidence map›Paper›PMID 40937856›Full record

ArticlemBio2025

The transcription factor RttA contributes to sterol regulation and azole resistance in

Lukas Birštonas, Peter Hortschansky, Ingo Bauer, Ervin M Alcanzo, Alexander Kühbacher, Birte Mertens, Christoph Müller, Axel A Brakhage, Fabio Gsaller

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lukas BirštonasInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Peter HortschanskyDepartment of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology (Leibniz-HKI), Jena, Germany.
Ingo BauerInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0002-3316-7769
Ervin M AlcanzoInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Alexander KühbacherInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Birte MertensInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Christoph MüllerDepartment of Pharmacy-Center for Drug Research, Ludwig-Maximilians-Universität München, Munich, Germany.
Axel A BrakhageDepartment of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology (Leibniz-HKI), Jena, Germany.ORCID 0000-0002-8814-4193
Fabio GsallerInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0002-9257-8648

Funding

Austrian Science Fund P35951
6 · The paper itself

Abstract

Major mechanisms of azole resistance in

Indexed as

Antifungal AgentsAspergillus fumigatusAzolesDrug Resistance, FungalFungal ProteinsGene Expression Regulation, FungalSterolsTranscription FactorsErgosterolAntifungal AgentsAzolesErgosterolFungal ProteinsSterolsTranscription FactorsAspergillus fumigatusazole resistanceergosterol biosynthesistranscription factor

Identifiers

PMID40937856
PMCPMC12505884

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.