Evidence map›Paper›PMID 40937723›Full record

ArticleJournal of the American Chemical Society2025

Optimizing the Synthesis of Deuterated Isotopomers and Isotopologues of Cyclohexene using Molecular Rotational Resonance Spectroscopy.

Justin T Weatherford-Pratt, Jacob A Smith, Martin S Holdren, Haley N Scolati, Reilly E Sonstrom, Megan N Ericson, Sarah E Brewster, Alvin Q Meng, Diane A Dickie, Brooks H Pate and 1 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Justin T Weatherford-PrattDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.
Jacob A SmithDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.
Martin S HoldrenDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.
Haley N ScolatiDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.
Reilly E SonstromDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.ORCID 0000-0003-0497-6660
Megan N EricsonDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.
Sarah E BrewsterDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.
Alvin Q MengDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.ORCID 0009-0006-1410-5980
Diane A DickieDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.ORCID 0000-0003-0939-3309
Brooks H PateDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.
W Dean HarmanDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.ORCID 0000-0003-0939-6980

Funding

Rapid Synthesis of Topologically Complex Molecules with Tungsten Dearomatization AgentsR35GM152065 · NIGMS · UNIVERSITY OF VIRGINIA · PI Walter Dean Harman · 2024 to 2026
$1.4M
Rapid Synthesis of Topologically Complex Molecules with Tungsten Dearomatization AgentsR01GM132205 · NIGMS · UNIVERSITY OF VIRGINIA · PI HARMAN, WALTER DEAN · 2019 to 2022
$1.3M
NIGMS NIH HHS R01 GM132205NIGMS NIH HHS R35 GM152065
6 · The paper itself

Abstract

Despite advances in reactions such as hydrogen isotope exchange (HIE) and reductive deuteration, achieving controlled and selective deuteration remains challenging. Moreover, the difficulty of developing successful deuteration platforms is compounded by a lack of means to assess the stereoisotopic purity of deuterated products. We previously reported a highly regio- and stereoselective approach for generating semideuterated cyclohexenes via tandem protonation (H

Identifiers

PMID40937723
PMCPMC12464997

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.