Evidence map›Paper›PMID 40937633›Full record

ArticleJournal of comparative effectiveness research2025

Matching-adjusted indirect comparisons of diroximel fumarate, ocrelizumab and interferon beta-1a for relapsing multiple sclerosis.

Carrie M Hersh, Yolanda Aladro-Benito, James B Lewin, Changyu Shen, Ivan Božin, Zhaonan Sun

Abstract readComparative Study
In one paragraph

Article in Journal of comparative effectiveness research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carrie M HershCleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV 89106, USA.ORCID 0000-0002-5716-5645
Yolanda Aladro-BenitoHospital Universitario de Getafe, Madrid, Spain.ORCID 0000-0001-9459-5452
James B LewinBiogen, Cambridge, MA 02142, USA.ORCID 0000-0002-2352-9113
Changyu ShenPreviously: Biogen, Cambridge, MA 02142, USA.ORCID 0000-0002-4444-0943
Ivan BožinBiogen, Baar, Switzerland.ORCID 0009-0008-2205-4233
Zhaonan SunBiogen, Cambridge, MA 02142, USA.ORCID 0000-0001-5333-4387

Funding

Validation of Serum Neurofilament Light Chain as a Prognostic and Monitoring Biomarker in Multiple SclerosisU01NS111678 · NINDS · JOHNS HOPKINS UNIVERSITY · PI CALABRESI, PETER A · 2020 to 2024
$6.3M
NINDS NIH HHS U01 NS111678
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibodies, Monoclonal, HumanizedImmunologic FactorsInterferon beta-1aMultiple Sclerosis, Relapsing-RemittingAdultClinical Trials, Phase III as TopicDisease ProgressionDouble-Blind MethodFemaleFumaratesHumansMaleMiddle AgedMulticenter Studies as TopicRandomized Controlled Trials as TopicTreatment OutcomeAntibodies, Monoclonal, Humanizeddiroximel fumarateFumaratesImmunologic FactorsInterferon beta-1aocrelizumabdiroximel fumarateinterferonmatching-adjusted indirect comparisonmultiple sclerosisocrelizumab

Identifiers

PMID40937633
PMCPMC12465943

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.