Evidence map›Paper›PMID 40937579›Full record

ArticleInternational journal of molecular medicine2025

Baicalin mitigates polycystic ovary syndrome‑associated non‑alcoholic fatty liver disease by inhibiting the AR/SREBP1 axis.

Bi-Hui Jin, Han Xu, Zi-Yan Zhang, Yu-Hang Fan, Chun-Yan Jiang, Shao-Long Qi, Chen-Yu Xiao, Xiao-Hua Fu, Ling-Bo Qian

Abstract read
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In one paragraph

Article in International journal of molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bi-Hui Jin *Center for Reproductive Medicine, Department of Reproductive Endocrinology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China.
Han Xu *Center for Reproductive Medicine, Department of Reproductive Endocrinology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China.
Zi-Yan ZhangDepartment of Physiology, School of Basic Medical Sciences and Forensic Medicine, Hangzhou Medical College, Hangzhou, Zhejiang 310053, P.R. China.
Yu-Hang FanDepartment of Reproductive Endocrinology, Center for Reproductive Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 315300, P.R. China.
Chun-Yan JiangDepartment of Physiology, School of Basic Medical Sciences and Forensic Medicine, Hangzhou Medical College, Hangzhou, Zhejiang 310053, P.R. China.
Shao-Long QiDepartment of Vascular Surgery, China‑Japan Union Hospital of Jilin University, Changchun, Jilin 130031, P.R. China.
Chen-Yu XiaoCenter for Reproductive Medicine, Department of Gynecology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China.
Xiao-Hua FuCenter for Reproductive Medicine, Department of Reproductive Endocrinology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China.
Ling-Bo QianDepartment of Physiology, School of Basic Medical Sciences and Forensic Medicine, Hangzhou Medical College, Hangzhou, Zhejiang 310053, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polycystic ovary syndrome (PCOS) is a common endocrine disorder frequently associated with metabolic disturbances, such as non‑alcoholic fatty liver disease (NAFLD), driven by hyperandrogenism‑induced lipogenesis. Baicalin (BA), a flavonoid derived from

Indexed as

FlavonoidsNon-alcoholic Fatty Liver DiseasePolycystic Ovary SyndromeReceptors, AndrogenSterol Regulatory Element Binding Protein 1AnimalsDisease Models, AnimalFemaleHumansLipid MetabolismLipogenesisLiverMiceMice, Inbred C57BLMolecular Docking SimulationSignal TransductionbaicalinFlavonoidsReceptors, AndrogenSrebf1 protein, mouseSterol Regulatory Element Binding Protein 1androgen receptorbaicalinlipid metabolismnon‑alcoholic fatty liver diseasepolycystic ovary syndromesterol regulatory element‑binding protein 1

Identifiers

PMID40937579
PMCPMC12440274

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.