Evidence map›Paper›PMID 40937565›Full record

ArticleMagnetic resonance in medicine2026

Ex vivo human brain volumetry: Validation of MRI measurements.

Amy Gérin-Lajoie, Walter Adame-Gonzalez, Eve-Marie Frigon, Liana Guerra Sanches, Anna Nayouf, Denis Boire, Mahsa Dadar, Josefina Maranzano

Abstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amy Gérin-LajoieDepartment of Anatomy, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, Canada.ORCID https://orcid.org/0009-0007-4292-5027
Walter Adame-GonzalezDepartment of Psychiatry, McGill University, Montreal, Quebec, Canada.
Eve-Marie FrigonDepartment of Anatomy, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, Canada.
Liana Guerra SanchesDepartment of Psychiatry, McGill University, Montreal, Quebec, Canada.
Anna NayoufDepartment of Anatomy, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, Canada.
Denis BoireDepartment of Anatomy, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, Canada.
Mahsa DadarDepartment of Psychiatry, McGill University, Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0003-4008-2672
Josefina MaranzanoDepartment of Anatomy, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, Canada.

Funding

CIHRFonds de recherche du Québec - Nature et technologiesNatural Sciences and Engineering Research Council of Canada
6 · The paper itself

Abstract

purposeThe volume of in vivo human brains is determined with various MRI measurement tools that have not been assessed against a gold standard. The purpose of this study was to validate the MRI brain volumes by scanning ex vivo, in situ specimens, which allows the extraction of the brain after the scan to compare its volume with the gold-standard water displacement method (WDM).

methodsThe 3T MRI T

resultsMean brain volumes, in cubic centimeters, were 1111.14 ± 121.78 for WDM, 1020.29 ± 70.01 for manual T

conclusionSynthSeg accurately determined the brain volume in ex vivo, in situ T

Indexed as

BrainImage Processing, Computer-AssistedMagnetic Resonance ImagingAdultDeep LearningFemaleGray MatterHumansMaleOrgan SizeReproducibility of ResultsWhite Matterex vivoMRIsegmentationvolumetrywater displacement

Identifiers

PMID40937565
PMCPMC12681294

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.